Acta Epileptologica
Scope & Guideline
Transforming epilepsy research through open access.
Introduction
Aims and Scopes
- Mechanisms of Epilepsy:
Research focused on understanding the biological, genetic, and molecular mechanisms underlying various forms of epilepsy, including biomolecular pathways, genetic mutations, and neurophysiological changes. - Clinical Management and Treatment:
Studies investigating the efficacy and safety of different therapeutic interventions, including pharmacological treatments, dietary therapies, and surgical options for managing epilepsy. - Patient-Centric Research:
Research emphasizing the quality of life, psychological impact, and social aspects of living with epilepsy, including stigma, comorbidities, and health-related quality of life. - Diagnostic Innovations:
Exploration of new diagnostic techniques and biomarkers for epilepsy, including advanced imaging methods and electrophysiological assessments. - Epidemiology and Risk Factors:
Studies examining the prevalence, risk factors, and demographic aspects of epilepsy across different populations, with a focus on understanding variations in incidence and access to care.
Trending and Emerging
- Personalized Medicine and Genetic Research:
An increasing emphasis on personalized treatment strategies based on genetic profiles and biomarkers, which is crucial for tailoring interventions for drug-resistant epilepsy. - Neurotechnology and Neuromodulation:
Growing interest in the application of neurotechnological advancements, including neuromodulation techniques such as vagus nerve stimulation and deep brain stimulation, for managing epilepsy. - Dietary and Lifestyle Interventions:
A notable trend towards exploring dietary therapies, particularly ketogenic diets, as alternative treatment options, reflecting a shift towards holistic management approaches. - Impact of Comorbidities on Epilepsy:
Research focusing on the psychological and social comorbidities associated with epilepsy, highlighting the importance of comprehensive care that addresses both neurological and psychosocial aspects. - Advanced Imaging and Biomarkers:
Emerging studies utilizing advanced imaging techniques and identifying biomarkers to better understand epilepsy mechanisms, improve diagnostics, and predict treatment outcomes.
Declining or Waning
- Traditional Pharmacological Approaches:
While pharmacological treatments remain a core focus, there is a noticeable decline in studies centered solely on traditional antiepileptic drugs, possibly due to the emergence of novel therapies and personalized medicine approaches. - Generalized Epilepsies:
Research specifically targeting generalized epilepsies appears to be waning, with more attention shifting towards focal epilepsy and drug-resistant cases, reflecting evolving clinical priorities. - Non-epileptic Seizures:
The focus on psychogenic non-epileptic seizures (PNES) is less prevalent, suggesting a potential decrease in interest or a shift towards integrating these studies within broader epilepsy research.
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