AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Scope & Guideline
Innovating the future of respiratory physiology.
Introduction
Aims and Scopes
- Lung Cellular and Molecular Physiology:
The journal publishes studies that investigate the fundamental cellular and molecular processes in lung physiology, including cellular signaling pathways, gene expression, and the role of various cell types in maintaining lung function. - Pathophysiology of Lung Diseases:
Research addressing the pathological mechanisms of lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and acute respiratory distress syndrome (ARDS) is a core focus, providing insights into disease mechanisms and potential therapeutic targets. - Respiratory Inflammation and Immunity:
The journal covers research on the immune responses in the lung, including inflammation, immune cell interactions, and the effects of environmental factors such as allergens and pollutants on lung health. - Innovative Therapeutic Approaches:
Research on novel therapeutic strategies, including stem cell therapies, bioengineering, and pharmacological interventions aimed at treating lung diseases, is a significant area of interest. - Translational Research:
The journal emphasizes studies that bridge basic research and clinical applications, aiming to translate findings from the laboratory to the bedside to improve patient outcomes in lung health.
Trending and Emerging
- Impact of COVID-19 on Lung Health:
There is a significant increase in research focusing on the effects of COVID-19 on lung physiology and pathology, including studies on acute lung injury, long-term pulmonary sequelae, and the interplay between COVID-19 and preexisting lung conditions. - Role of Extracellular Vesicles:
Research on the role of extracellular vesicles in lung health and disease is gaining traction, highlighting their potential as biomarkers and therapeutic targets in conditions such as COPD and pulmonary fibrosis. - Sex Differences in Lung Disease:
An emerging theme is the exploration of sex differences in lung physiology and disease response, recognizing the need to understand how biological sex influences lung health outcomes. - Environmental and Lifestyle Factors:
There is a growing emphasis on the impact of environmental exposures, such as pollution and e-cigarette use, on lung health, reflecting a broader interest in how lifestyle choices affect respiratory diseases. - Stem Cell and Regenerative Medicine Approaches:
Innovations in stem cell research and regenerative medicine aimed at repairing lung tissue and restoring function are increasingly featured, indicating a shift towards potential curative therapies.
Declining or Waning
- Basic Animal Models:
There has been a noticeable decrease in studies utilizing basic animal models for lung research, as the field increasingly emphasizes translational research that directly relates to human health and disease. - Non-invasive Techniques:
Research employing traditional non-invasive measurement techniques for lung function and pathology seems to be waning, potentially replaced by advanced imaging and molecular techniques that offer higher resolution and specificity. - Historical Perspectives on Lung Diseases:
Papers focusing on historical perspectives or reviews of past research trends in lung diseases appear to be less frequent, indicating a shift towards more contemporary and forward-looking studies.
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