CIRCULATION RESEARCH

Scope & Guideline

Leading the way in cardiovascular research since 1953.

Introduction

Immerse yourself in the scholarly insights of CIRCULATION RESEARCH with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN0009-7330
PublisherLIPPINCOTT WILLIAMS & WILKINS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1953 to 2024
AbbreviationCIRC RES / Circ.Res.
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressTWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103

Aims and Scopes

Circulation Research is dedicated to advancing cardiovascular science through innovative research that spans basic, translational, and clinical domains. The journal focuses on the molecular and cellular mechanisms underlying cardiovascular health and disease, including the intersection of cardiovascular and systemic diseases.
  1. Cardiovascular Biology and Physiology:
    Research exploring the fundamental biological processes and physiological mechanisms that govern cardiovascular function, including cardiac muscle function, endothelial biology, and vascular dynamics.
  2. Pathophysiology of Cardiovascular Diseases:
    Studies investigating the molecular and cellular mechanisms involved in various cardiovascular diseases such as heart failure, myocardial infarction, atherosclerosis, and arrhythmias.
  3. Translational Research:
    Research aimed at translating basic scientific discoveries into clinical applications, including the development of new therapeutic strategies and interventions for cardiovascular diseases.
  4. Innovative Therapeutic Approaches:
    Exploration of novel therapeutic modalities, including gene therapy, stem cell therapy, and advanced biomaterials for cardiovascular repair and regeneration.
  5. Environmental and Lifestyle Factors in Cardiovascular Health:
    Research assessing the impact of environmental exposures, lifestyle choices, and metabolic factors on cardiovascular health and disease progression.
  6. Immunology and Inflammation in Cardiovascular Diseases:
    Investigations into the roles of immune cells and inflammatory processes in the development and progression of cardiovascular conditions.
  7. Genomics and Personalized Medicine:
    Studies leveraging genetic and genomic insights to understand individual variations in cardiovascular disease risk and response to therapies.
Circulation Research has witnessed significant shifts in research focus, with several emerging themes gaining prominence in recent publications. These trends reflect the journal's commitment to addressing contemporary challenges in cardiovascular science.
  1. Single-Cell and Multi-Omics Approaches:
    An increasing number of studies are utilizing single-cell RNA sequencing and multi-omics approaches to unravel the complex cellular heterogeneity and molecular mechanisms underlying cardiovascular diseases.
  2. Cardiac Regeneration and Repair:
    Research into cardiac regeneration, including the potential of stem cells and engineered tissues, is gaining traction, driven by the need for innovative treatments for heart failure and myocardial infarction.
  3. Microbiome and Cardiovascular Interactions:
    Emerging evidence highlights the significant role of gut microbiota in modulating cardiovascular health, with studies exploring how microbial metabolites influence cardiac function and disease.
  4. Inflammation and Immunology:
    There is a growing focus on the role of inflammation and immune responses in cardiovascular diseases, with research investigating the interactions between immune cells and cardiovascular tissues.
  5. Mitochondrial Biology and Metabolism:
    Increased attention is being given to mitochondrial function and bioenergetics in the context of cardiovascular health, emphasizing the importance of metabolic pathways in disease mechanisms.
  6. Artificial Intelligence and Machine Learning:
    The application of artificial intelligence and machine learning techniques to analyze complex cardiovascular data sets is on the rise, aiding in risk prediction and personalized treatment strategies.

Declining or Waning

While Circulation Research continues to evolve, certain traditional themes have seen a decline in focus over recent years, reflecting shifts in research priorities and emerging trends in cardiovascular science.
  1. Traditional Pharmacology:
    Research centered on conventional pharmacological interventions for cardiovascular diseases has become less prominent, as the field increasingly embraces innovative therapeutic strategies such as gene therapy and personalized medicine.
  2. Basic Animal Models of Cardiovascular Disease:
    There is a noticeable decline in studies utilizing classical animal models in favor of more sophisticated models, including human-induced pluripotent stem cell (hiPSC) systems and organ-on-a-chip technologies.
  3. Purely Descriptive Studies:
    The journal has moved away from purely descriptive studies of cardiovascular conditions, focusing instead on mechanistic insights and translational applications that provide clear therapeutic implications.
  4. Static Imaging Techniques:
    The reliance on traditional static imaging techniques is diminishing as dynamic and advanced imaging modalities, such as multimodal imaging and real-time imaging, become more prevalent in cardiovascular research.

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