CLINICAL SCIENCE

Scope & Guideline

Advancing the Frontiers of Clinical Knowledge

Introduction

Welcome to your portal for understanding CLINICAL SCIENCE, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN0143-5221
PublisherPORTLAND PRESS LTD
Support Open AccessNo
CountryUnited Kingdom
TypeJournal
Convergefrom 1946 to 1949, from 1951 to 1959, 1973, from 1979 to 2024
AbbreviationCLIN SCI / Clin. Sci.
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address1ST FLR, 10 QUEEN STREET PLACE, LONDON EC4R 1BE, ENGLAND

Aims and Scopes

The journal Clinical Science focuses on advancing the understanding of clinical and translational research, particularly in the areas of cardiovascular, renal, and metabolic diseases. It emphasizes the integration of laboratory findings with clinical applications, providing insights that can improve patient outcomes.
  1. Cardiovascular Research:
    This area explores the mechanisms underlying cardiovascular diseases, including hypertension, heart failure, and the impact of metabolic disorders on cardiovascular health.
  2. Renal Physiology and Pathology:
    The journal covers research on kidney function, injury, and diseases, including diabetic nephropathy and acute kidney injury, with a focus on molecular and cellular mechanisms.
  3. Metabolic Disorders and Obesity:
    Research on the pathophysiology of obesity, diabetes, and associated metabolic syndromes, examining how these conditions affect cardiovascular and renal health.
  4. Inflammation and Immunology:
    The journal addresses the role of inflammation in various diseases, including cardiovascular and renal disorders, and how immune responses can influence disease progression.
  5. Translational Medicine:
    Clinical Science emphasizes the translation of basic research findings into clinical practice, focusing on therapeutic innovations and their implementation in patient care.
  6. Molecular Mechanisms of Disease:
    Research on the molecular and genetic factors contributing to diseases, including cancer, cardiovascular, and metabolic disorders, highlighting potential therapeutic targets.
  7. Sex Differences in Disease:
    The journal investigates how biological sex influences the pathophysiology and treatment responses in various diseases, particularly in cardiovascular and metabolic health.
The journal Clinical Science has shown a dynamic evolution in its focus areas, with several emerging themes gaining traction. These trends reflect the journal's responsiveness to current challenges in clinical research and healthcare.
  1. Endothelin System Research:
    There has been a significant increase in studies focusing on the endothelin system, particularly its role in cardiovascular and renal diseases, highlighting its potential as a therapeutic target.
  2. Microbiome and Gut Health:
    Research on the gut microbiome's influence on metabolic and cardiovascular health is emerging as a vital area, with studies exploring its role in disease mechanisms and therapeutic interventions.
  3. Personalized and Precision Medicine:
    There is a growing emphasis on precision medicine approaches that tailor treatments based on individual patient profiles, integrating genetic, biomarker, and lifestyle factors.
  4. Neurovascular Interactions:
    Emerging studies are increasingly investigating the connections between neurological and cardiovascular health, emphasizing the importance of understanding these interrelationships in disease prevention and treatment.
  5. Inflammation and Immunotherapy:
    Research on the role of inflammation in chronic diseases and the potential of immunotherapeutic strategies is gaining interest, reflecting a broader trend in treating complex conditions.
  6. Sex-Specific Research:
    There is an upward trend in research addressing sex differences in disease manifestation and treatment responses, which is crucial for developing more effective and tailored healthcare strategies.

Declining or Waning

While Clinical Science continues to evolve, certain themes appear to be declining in prominence based on recent publications. These waning scopes may reflect shifts in research priorities or advancements in specific areas.
  1. Traditional Pharmacological Approaches:
    There is a noticeable decline in studies focusing solely on conventional pharmacological interventions, as the field shifts toward more integrated and personalized medicine approaches.
  2. Basic Science without Clinical Relevance:
    Research that does not bridge the gap between basic science and clinical applications is becoming less prevalent, indicating a stronger emphasis on translational efforts.
  3. Single-Factor Studies:
    The trend is moving away from studies that examine single factors in isolation, such as individual biomarkers, towards more complex, multifactorial approaches that consider interactions within biological systems.
  4. Non-Human Model Studies:
    There has been a decrease in the publication of studies relying solely on non-human models, as there is a growing demand for research that directly translates to human health and disease outcomes.

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