Familial Cancer
Scope & Guideline
Bridging the gap between genetics and patient care.
Introduction
Aims and Scopes
- Genetic predisposition to cancer:
The journal emphasizes research on hereditary cancer syndromes, including the identification and characterization of genetic variants associated with increased cancer risk. - Screening and surveillance strategies:
A core area of focus is the development and evaluation of screening protocols for high-risk individuals, particularly those with familial cancer syndromes like Lynch syndrome and hereditary breast and ovarian cancer. - Clinical management and interventions:
The journal addresses clinical strategies for the management of hereditary cancers, including risk-reducing surgeries, chemoprevention, and personalized treatment approaches based on genetic profiles. - Psychosocial aspects of genetic testing:
Research on the psychological impact of genetic testing and the experiences of patients and families navigating hereditary cancer risk is an important theme, highlighting the need for supportive care. - Policy and healthcare delivery:
The journal also explores healthcare policy implications and the integration of genetic testing into clinical practice, focusing on improving access and equity in cancer care.
Trending and Emerging
- Integration of genomic technologies:
Recent studies increasingly utilize advanced genomic techniques, such as whole genome sequencing and multi-gene panels, to identify hereditary cancer syndromes and characterize variants, reflecting the growing importance of precision medicine. - Cascade testing and family communication:
There is a rising emphasis on cascade genetic testing and the psychosocial dynamics of communicating genetic risk within families, highlighting the importance of family involvement in hereditary cancer management. - Health disparities and access to care:
Emerging themes include the examination of health disparities in access to genetic testing and cancer care, particularly among underrepresented populations, which is critical for equitable healthcare delivery. - Long-term outcomes and survivorship:
Studies focusing on long-term outcomes for individuals with hereditary cancer syndromes, including survivorship issues and quality of life, are becoming more prominent, addressing the holistic needs of patients post-diagnosis. - Digital health innovations:
The integration of digital health tools for cancer risk assessment and genetic counseling is a trending area of research, reflecting a shift towards technology-driven solutions in healthcare.
Declining or Waning
- Non-genetic factors in cancer risk:
There has been a noticeable decrease in studies focusing on environmental or lifestyle factors contributing to familial cancer risk, suggesting a shift towards more genetic and molecular investigations. - Rare cancer syndromes:
Research on less common hereditary cancer syndromes, while still relevant, has seen a decline in frequency, as the journal's focus has increasingly gravitated towards more prevalent syndromes like Lynch syndrome and BRCA-related cancers. - General population studies:
The journal appears to be moving away from large-scale studies of general populations in favor of targeted research in specific high-risk groups, potentially reducing the breadth of its epidemiological coverage.
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