JOURNAL OF BONE AND MINERAL RESEARCH
Scope & Guideline
Pioneering research at the crossroads of endocrinology and orthopedics.
Introduction
Aims and Scopes
- Bone Health and Disease Mechanisms:
Research encompassing the biological, genetic, and molecular mechanisms underlying bone health, osteoporosis, and related disorders such as osteogenesis imperfecta and fibrodysplasia ossificans progressiva. - Clinical Research and Treatment Efficacy:
Clinical studies evaluating the efficacy and safety of treatments for bone diseases, including bisphosphonates, teriparatide, and newer agents like romosozumab, especially in populations at risk. - Diagnostics and Screening:
Advancements in diagnostic techniques for bone-related conditions, including the use of imaging technologies like HR-pQCT and machine learning algorithms for fracture risk assessment. - Genetic and Molecular Studies:
Investigations into genetic predispositions to bone diseases and the role of specific genes in bone metabolism, including studies on gene therapy and pharmacogenomics. - Lifestyle and Environmental Factors:
Research examining how factors such as diet, exercise, and environmental influences affect bone health and the risk of fractures. - Pediatric and Geriatric Bone Health:
Studies focused on bone health across different age groups, including childhood conditions like osteogenesis imperfecta and the impact of aging on bone density and quality.
Trending and Emerging
- Artificial Intelligence and Machine Learning Applications:
The integration of AI and machine learning in diagnostics and treatment predictions for osteoporosis and fractures is gaining traction, highlighting the journal's commitment to modern methodologies. - Multi-Omics Approaches:
Research employing multi-omics approaches to understand bone metabolism and diseases at a more granular level is on the rise, showcasing the complexity of bone health. - Impact of Gut Microbiome on Bone Health:
Studies exploring the relationship between gut microbiota and bone health are emerging, suggesting a novel avenue for understanding systemic influences on bone metabolism. - Personalized Medicine and Genetic Insights:
A growing emphasis on personalized medicine, including pharmacogenomics and the genetic basis of bone diseases, is evident in recent publications. - Longitudinal Studies on Bone Health:
Increased focus on longitudinal studies that track changes in bone health over time, particularly in relation to lifestyle factors and disease progression, is becoming more common.
Declining or Waning
- Traditional Osteoporosis Therapies:
Research on older osteoporosis treatment methods, such as hormonal replacement therapy, has decreased as new, more effective therapies emerge and shift the focus of research towards novel agents. - Basic Science Studies Without Clinical Relevance:
There is a noticeable reduction in the publication of basic science studies that do not translate into clinical applications, as the journal increasingly emphasizes translational research. - Epidemiological Studies Without Novel Insights:
Epidemiological studies that do not provide new insights or significant advancements in understanding fracture risks or bone health are becoming less prominent.
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