JOURNAL OF NATURAL PRODUCTS
Scope & Guideline
Transforming Natural Resources into Scientific Knowledge
Introduction
Aims and Scopes
- Natural Product Chemistry:
The journal emphasizes the chemistry of natural products, including their isolation, structural elucidation, and synthesis. This encompasses a wide array of compounds such as terpenoids, alkaloids, flavonoids, and polyketides. - Biological Activity and Pharmacology:
A core focus is on the biological activities of natural products, including their roles as antimicrobial, anti-inflammatory, anticancer, and neuroprotective agents. The journal publishes studies demonstrating the pharmacological effects of these compounds. - Biosynthesis and Metabolic Pathways:
Research on the biosynthesis of natural products, including genetic and enzymatic pathways involved in their production, is a significant aspect. This includes studies on gene clusters and metabolic engineering. - Computational and Analytical Approaches:
The journal supports the use of computational methods for predicting the properties and activities of natural products. Analytical techniques such as NMR, LC-MS, and molecular networking are frequently utilized to characterize compounds. - Sustainable Sourcing and Applications:
Research on sustainable practices in the sourcing of natural products and their applications in health, agriculture, and industry is increasingly prominent, reflecting a growing awareness of environmental and ethical considerations.
Trending and Emerging
- Targeted Drug Discovery:
There is a significant increase in research that focuses on the targeted discovery of natural products as potential drug candidates, including studies on specific diseases and therapeutic targets, particularly in cancer and infectious diseases. - Natural Product Synergy and Combinatorial Approaches:
Emerging studies are exploring the synergistic effects of natural products when used in combination, particularly in the context of enhancing therapeutic efficacy and overcoming drug resistance. - Biotechnology and Synthetic Biology Applications:
The integration of biotechnology, including genetic manipulation and synthetic biology, is increasingly being employed to enhance the production of valuable natural products, indicating a trend towards leveraging biotechnological innovations. - Environmental and Ecological Impact Studies:
Research assessing the ecological impacts of natural products, including their roles in ecosystems and potential environmental applications, is gaining attention, reflecting a broader interest in sustainability. - Cannabinoid Research:
The exploration of cannabinoids and their derivatives, particularly in relation to their therapeutic potential for various conditions, including pain, inflammation, and neurological disorders, is a rapidly growing area of interest.
Declining or Waning
- Traditional Medicinal Plants:
There has been a noticeable decline in studies focused solely on traditional medicinal plants without further exploration into their active compounds or mechanisms of action. This shift suggests a move towards more mechanistic and bioactive-focused research. - Synthetic Natural Products with Limited Biological Evaluation:
Papers that primarily report the synthetic pathways of natural products without comprehensive biological evaluation or application are less frequently published. There is a trend towards emphasizing the biological relevance of synthetic efforts. - Basic Phytochemical Surveys:
Basic surveys of phytochemical constituents without detailed analysis of biological activity or potential applications have become less prevalent, indicating a preference for studies that connect chemistry with pharmacology.
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