JBMR Plus
Scope & Guideline
Exploring the forefront of metabolic and orthopedic science.
Introduction
Aims and Scopes
- Bone Biology and Physiology:
Research focusing on the fundamental biological processes of bone formation, remodeling, and metabolism, including studies on osteoblasts, osteoclasts, and osteocytes. - Bone Diseases and Disorders:
Investigations into various bone diseases such as osteoporosis, osteogenesis imperfecta, and hypophosphatasia, including their pathophysiology, clinical manifestations, and treatment options. - Clinical Trials and Interventions:
Reports on clinical trials assessing the efficacy and safety of pharmacological and non-pharmacological interventions for bone health, including bisphosphonates, parathyroid hormone analogs, and dietary supplements. - Imaging and Biomarkers:
Studies utilizing imaging techniques (e.g., HR-pQCT, DXA) and biomarkers to assess bone quality, density, and turnover, contributing to the understanding of fracture risk and treatment outcomes. - Genetic and Molecular Mechanisms:
Exploration of the genetic, epigenetic, and molecular pathways influencing bone health and disease, including the role of microRNAs, signaling pathways, and genetic variants. - Public Health and Epidemiology:
Research addressing public health aspects of bone health, including epidemiological studies on fracture incidence, risk factors, and the impact of lifestyle and environmental factors on bone health.
Trending and Emerging
- Microbiome and Bone Health:
Emerging studies highlight the relationship between gut microbiota and bone health, exploring how dietary components and microbiome alterations can affect bone metabolism. - Personalized Medicine in Osteoporosis:
There is an increasing focus on tailoring osteoporosis treatments based on genetic, phenotypic, and lifestyle factors, indicating a shift towards personalized approaches in managing bone diseases. - Digital Health and Osteoporosis Screening:
The integration of digital technologies and machine learning in osteoporosis risk assessment and screening is gaining traction, particularly in improving access and accuracy in clinical settings. - Inflammation and Bone Disease:
Research increasingly investigates the role of inflammatory processes in bone diseases, linking systemic inflammation to conditions like osteoporosis and osteoarthritis. - Nutritional Interventions:
A growing body of literature is examining the impact of specific dietary patterns, supplements, and functional foods on bone health, reflecting a trend towards preventive and integrative health strategies.
Declining or Waning
- Vitamin D Research:
While vitamin D is crucial for bone health, the volume of studies focusing solely on vitamin D supplementation and its direct effects on bone density has decreased, possibly due to previous extensive literature. - Traditional Osteoporosis Treatments:
Research on older treatments like estrogen replacement therapy and traditional bisphosphonates is declining, as newer therapies and combination approaches gain prominence. - Animal Models of Bone Disease:
There seems to be a reduction in studies using traditional animal models for bone disease, possibly shifting towards more clinically relevant human studies or advanced models. - Basic Science of Bone Mechanotransduction:
Research focused on the basic cellular mechanisms of how mechanical forces affect bone cells has seen less emphasis, as the field moves towards integrative approaches combining biomechanics and biology.
Similar Journals
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Diabetology International
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