World Journal of Hepatology
Scope & Guideline
Exploring the complexities of liver diseases worldwide.
Introduction
Aims and Scopes
- Liver Diseases and Disorders:
The journal publishes research on various liver diseases, including hepatitis, cirrhosis, hepatocellular carcinoma, and metabolic liver diseases, exploring their pathogenesis, epidemiology, and clinical management. - Innovative Therapeutic Approaches:
Research on novel therapeutic strategies, including pharmacological treatments, surgical interventions, and emerging therapies such as immunotherapy and gene therapy for liver diseases. - Diagnostic Advances:
Focus on advancements in diagnostic methodologies, including imaging techniques, biomarkers, and non-invasive assessments for liver diseases, aiding in early detection and management. - Microbiome and Liver Health:
Exploration of the gut-liver axis, including the role of gut microbiota in liver diseases and the potential of microbiome modulation as a therapeutic strategy. - Public Health and Epidemiology:
Studies that address the public health implications of liver diseases, including epidemiological studies, health disparities, and the impact of socio-economic factors on liver health. - Clinical Outcomes and Quality of Life:
Research on patient outcomes, quality of life assessments, and the psychosocial aspects of living with liver diseases, including post-transplant care.
Trending and Emerging
- Metabolic Dysfunction-Associated Liver Diseases:
An increased focus on metabolic dysfunction-associated fatty liver disease (MAFLD) highlights an evolving understanding of liver diseases linked to metabolic disorders, with implications for diagnosis and treatment. - COVID-19 and Liver Health:
Research relating to the impact of COVID-19 on liver health, including liver injury in infected patients and management strategies for liver disease during the pandemic, has surged. - Immunotherapy and Precision Medicine:
There is a growing interest in immunotherapy for hepatocellular carcinoma and other liver malignancies, alongside precision medicine approaches tailored to individual patient profiles. - Gut-Liver Axis Research:
Emerging studies on the interplay between gut microbiota and liver health suggest a significant role of the microbiome in liver disease progression and treatment responses. - Artificial Intelligence and Machine Learning:
The application of AI and machine learning in predicting outcomes and improving diagnostic accuracy in liver diseases is gaining traction, showcasing technological advancements in hepatology.
Declining or Waning
- Traditional Herbal Remedies:
Research on traditional herbal treatments for liver diseases has decreased, reflecting a shift towards more evidence-based pharmacological approaches and clinical trials. - Basic Science Research:
While foundational research remains important, there has been a noticeable decline in studies focused solely on basic science without clear clinical implications, as the journal moves towards more translational research. - Single-Center Case Reports:
The frequency of single-center case reports has declined, possibly due to a preference for larger, multicenter studies that provide more generalizable data.
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