ACS Pharmacology & Translational Science
Scope & Guideline
Driving breakthroughs from bench to bedside.
Introduction
Aims and Scopes
- Pharmacological Research:
The journal emphasizes original research articles that explore pharmacological mechanisms, drug interactions, and therapeutic effects of various compounds. - Translational Science:
It focuses on studies that translate basic research findings into clinical applications, including the development of new therapeutic strategies and the evaluation of drug efficacy in clinical settings. - Drug Discovery and Development:
The journal publishes articles related to innovative drug discovery techniques, including the design, synthesis, and evaluation of new pharmacological agents. - Mechanistic Studies:
Research that elucidates the biochemical and molecular mechanisms underlying drug action and disease processes is a key focus. - Novel Therapeutic Approaches:
The journal seeks to highlight new methodologies and technologies in the treatment of various diseases, including cancer, neurodegenerative disorders, and infectious diseases. - Interdisciplinary Research:
It encourages interdisciplinary studies that incorporate insights from pharmacology, medicinal chemistry, biology, and clinical research.
Trending and Emerging
- Nanomedicine and Drug Delivery Systems:
Recent publications emphasize the development of novel nanocarriers for targeted drug delivery, improving therapeutic efficacy while minimizing side effects. - Immunotherapy and Cancer Treatment:
A growing number of studies focus on immunotherapeutic approaches, including the development of immune checkpoint inhibitors and personalized cancer vaccines, reflecting a shift towards harnessing the immune system in cancer treatment. - Psychedelic Research and Mental Health:
Research into the therapeutic effects of psychedelics for mental health disorders is gaining traction, indicating a renewed interest in alternative treatment modalities. - Precision Medicine and Pharmacogenomics:
There is an increasing emphasis on personalized medicine approaches, exploring genetic factors that influence drug response and tailoring therapies to individual patient profiles. - Microbiome and Pharmacology:
Emerging studies investigate the gut microbiome's impact on drug metabolism and efficacy, highlighting the importance of microbiome interactions in pharmacology. - SARS-CoV-2 and COVID-19 Therapeutics:
The ongoing pandemic has spurred a significant increase in research focused on antiviral therapies, vaccine development, and understanding the mechanisms of SARS-CoV-2, reflecting a timely response to a global health crisis.
Declining or Waning
- Traditional Pharmacology:
There has been a noticeable decline in research focused solely on traditional pharmacological studies without translational implications, as the journal increasingly prioritizes studies that connect laboratory findings to clinical applications. - Single-Disease Focused Studies:
Research that solely targets a single disease without considering broader implications or multi-target approaches is becoming less prominent, as interdisciplinary and integrative studies gain more interest. - Basic Biochemical Mechanism Studies:
While foundational research is essential, there has been a shift away from purely biochemical studies that do not lead to translational insights or therapeutic innovations.
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