Advances in Pharmacological and Pharmaceutical Sciences
Scope & Guideline
Advancing the Frontiers of Drug Discovery.
Introduction
Aims and Scopes
- Pharmacological Research:
Focuses on the investigation of the mechanisms of action, efficacy, and safety of various pharmacological agents, including natural products and synthetic compounds. - Pharmaceutical Formulations:
Covers the development and optimization of drug formulations, including novel delivery systems, biopharmaceuticals, and dosage forms. - Ethnopharmacology and Traditional Medicine:
Explores the medicinal properties of plants and traditional remedies, integrating ethnobotanical knowledge with modern pharmacological research. - Toxicology and Safety Assessments:
Investigates the safety and toxicological properties of drugs and natural products, including in vitro and in vivo studies. - Clinical Pharmacology:
Addresses the clinical implications of pharmacological therapies, including pharmacokinetics, pharmacodynamics, and drug interactions. - Pharmacogenomics and Personalized Medicine:
Examines the role of genetic factors in drug response, aiming to advance personalized therapeutic approaches. - Innovative Drug Discovery:
Focuses on novel methodologies and technologies in drug discovery, including molecular docking, high-throughput screening, and systems pharmacology.
Trending and Emerging
- Nanotechnology in Drug Delivery:
An increasing number of publications are focusing on the use of nanotechnology to enhance drug delivery systems, improve bioavailability, and target therapies more effectively. - Synergistic Effects of Natural Compounds:
There is a growing interest in exploring the synergistic effects of combinations of natural products, particularly in anti-inflammatory and antimicrobial contexts. - Pharmacogenomics and Tailored Therapies:
Research in pharmacogenomics is on the rise, focusing on how genetic variations affect individual responses to drugs, paving the way for personalized medicine. - In Silico Drug Discovery:
The integration of computational methods in drug discovery processes is gaining traction, with an emphasis on molecular docking and predictive modeling to identify potential therapeutic agents. - Clinical Implications of Herbal Medicines:
An increase in studies examining the clinical efficacy and safety of herbal medicines, particularly in the context of chronic diseases and multi-drug regimens, is emerging as a significant theme. - Regenerative Medicine and Pharmacology:
Emerging research is focusing on the pharmacological aspects of regenerative medicine, particularly in the context of stem cell therapies and tissue engineering.
Declining or Waning
- Conventional Medicinal Uses of Plants:
There has been a noticeable reduction in papers focusing solely on traditional uses of medicinal plants without accompanying pharmacological validation or modern methodologies. - Basic Pharmacokinetics Studies:
Research articles dedicated exclusively to fundamental pharmacokinetic studies, without integration into clinical or translational contexts, are becoming less common. - Chemistry of Natural Products:
While the chemistry of natural products remains important, standalone studies focusing mainly on chemical composition, without linking to pharmacological effects, are decreasing. - Animal Studies with Limited Clinical Relevance:
There is a trend away from animal studies that do not have a clear translational pathway to human health or clinical applications.
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