AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Scope & Guideline

Connecting Molecular Biology to Clinical Practice

Introduction

Welcome to the AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN1350-6129
PublisherTAYLOR & FRANCIS LTD
Support Open AccessNo
CountryUnited Kingdom
TypeJournal
Convergefrom 1994 to 2024
AbbreviationAMYLOID / Amyloid-J. Protein Fold. Disord.
Frequency4 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND

Aims and Scopes

The AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS focuses on advancing the understanding of amyloidosis and protein folding disorders through innovative research. The journal serves as a platform for the dissemination of findings that improve diagnosis, treatment, and management of amyloid-related diseases.
  1. Understanding Amyloid Diseases:
    The journal emphasizes the study of various forms of amyloidosis, including AL, ATTR, and AA amyloidosis, exploring their molecular mechanisms, clinical presentations, and diagnostic challenges.
  2. Innovative Diagnostic Techniques:
    Methodologies such as mass spectrometry, imaging techniques, and biomarker discovery are frequently discussed, highlighting advancements in the detection and characterization of amyloid deposits.
  3. Therapeutic Advances:
    Research on treatment modalities, including pharmacological interventions like tafamidis and patisiran, is a core area, focusing on their efficacy, safety, and pharmacodynamics in different patient populations.
  4. Multidisciplinary Approaches:
    The journal promotes a multidisciplinary perspective, integrating insights from genetics, pathology, neurology, cardiology, and proteomics to provide a comprehensive understanding of amyloidosis.
  5. Patient-Centric Research:
    Studies that address patient experiences, outcomes, and the impact of amyloidosis on quality of life are essential, emphasizing the importance of patient-reported outcomes in clinical research.
The landscape of amyloidosis research is evolving, with several emerging themes gaining traction in recent publications. This reflects a growing focus on precision medicine, novel therapeutic strategies, and improved diagnostic techniques.
  1. Precision Medicine Approaches:
    There is a significant trend towards personalized treatment strategies for amyloidosis patients, using genetic profiling and biomarkers to tailor therapies, particularly in hereditary forms of the disease.
  2. Neurodegenerative Links:
    Research increasingly explores the connections between amyloidosis and neurodegenerative diseases, particularly in understanding the role of amyloid deposits in conditions like Alzheimer's disease.
  3. Longitudinal Studies and Real-World Evidence:
    Emerging trends include a focus on longitudinal studies that assess treatment outcomes over time, providing valuable real-world evidence on the effectiveness of therapies.
  4. Innovative Imaging Techniques:
    Advancements in imaging modalities, such as PET and MRI, are becoming increasingly relevant for both diagnosis and monitoring of disease progression in amyloidosis.
  5. Patient-Reported Outcomes and Quality of Life:
    There is a growing emphasis on incorporating patient-reported outcomes into research, reflecting a broader recognition of the importance of quality of life for individuals living with amyloidosis.

Declining or Waning

While the journal continues to expand its focus on numerous aspects of amyloidosis, certain themes appear to be declining in prominence. This may reflect shifts in research priorities or advancements in understanding that lessen the need for certain investigations.
  1. Historical Case Studies:
    There has been a noticeable reduction in publications focusing on historical case reports of amyloidosis, suggesting a move towards more contemporary research and clinical trials.
  2. Basic Science of Protein Folding:
    Research primarily centered on fundamental aspects of protein folding without direct clinical or therapeutic implications seems to be waning, as the journal prioritizes studies with immediate clinical relevance.
  3. Epidemiological Studies:
    While still present, there is a decrease in the frequency of large-scale epidemiological studies on amyloidosis prevalence, indicating a possible shift towards more localized, specific studies or clinical trials.
  4. Iatrogenic Amyloidosis Reports:
    Reports concerning iatrogenic forms of amyloidosis, although significant, are appearing less frequently, which may reflect advancements in clinical practices that reduce such occurrences.
  5. Animal Models in Amyloidosis Research:
    Research utilizing animal models to study amyloidosis mechanisms is declining, possibly as the field shifts towards human-centric studies that yield more applicable results.

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