BIOCHEMICAL GENETICS
Scope & Guideline
Innovating the Understanding of Genetic Mechanisms
Introduction
Aims and Scopes
- Cancer Genomics and Epigenetics:
The journal frequently publishes studies exploring genetic variations, gene expression, and epigenetic modifications associated with various cancers. This includes research on biomarkers for diagnosis, prognosis, and therapeutic targets. - Molecular Mechanisms of Disease:
Research focusing on the molecular pathways involved in disease processes, including genetic, epigenetic, and environmental factors that contribute to conditions such as diabetes, cardiovascular diseases, and neurodegenerative disorders. - MicroRNA and Long Non-Coding RNA Functions:
A significant portion of the research is dedicated to understanding the roles of microRNAs and long non-coding RNAs in gene regulation, cancer progression, and other critical biological processes. - Genetic Diversity and Population Genetics:
The journal also emphasizes studies on genetic diversity, population structure, and the implications of genetic variations in different populations, particularly in relation to health and disease susceptibility. - Bioinformatics and Computational Biology:
There is a strong focus on bioinformatics approaches to analyze genetic data, identify potential biomarkers, and understand complex genetic interactions and regulatory networks.
Trending and Emerging
- Machine Learning and Artificial Intelligence in Genetics:
There is an increasing trend towards employing machine learning and AI techniques for analyzing genetic data, predicting disease outcomes, and identifying novel biomarkers, enhancing the precision of genetic studies. - Cuproptosis and Ferroptosis Research:
Emerging studies on cell death mechanisms, particularly cuproptosis and ferroptosis, are gaining attention for their implications in cancer treatment and understanding cellular stress responses. - Immune-Related Genetic Studies:
Research focusing on the genetic basis of immune responses, particularly in the context of cancer immunotherapy and autoimmune diseases, is becoming more prominent, highlighting the interplay between genetics and immunology. - Long Non-Coding RNAs and Circular RNAs:
The exploration of long non-coding RNAs and circular RNAs in gene regulation and their roles in various diseases is a rapidly growing area, reflecting a shift towards understanding the complexities of non-coding RNA functions. - Environmental and Epigenetic Influences on Genetics:
Studies examining how environmental factors affect gene expression and contribute to disease susceptibility are increasingly prevalent, emphasizing the importance of epigenetics in genetic research.
Declining or Waning
- Traditional Genetic Mapping Studies:
There has been a noticeable decline in papers focusing solely on traditional genetic mapping techniques, as newer methodologies such as genome-wide association studies (GWAS) and next-generation sequencing have gained prominence. - Basic Biochemical Studies Without Genetic Context:
Research that focuses purely on biochemical processes without a genetic or genomic context is becoming less common, as the field increasingly integrates molecular genetics with biochemistry. - Single Gene Studies:
Studies that concentrate on the effects of single genes on phenotypes are being overshadowed by more comprehensive approaches that consider gene networks, epigenetics, and environmental interactions.
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