MOLECULAR BIOLOGY
Scope & Guideline
Elevating Academic Excellence in Molecular Research
Introduction
Aims and Scopes
- Molecular Mechanisms of Gene Regulation:
Research exploring transcriptional and translational regulation, including the roles of transcription factors, chromatin remodeling, and non-coding RNAs. - Protein Function and Interactions:
Studies investigating protein structure, function, interactions, and post-translational modifications, highlighting their roles in cellular pathways. - Genetic Engineering and Biotechnology:
Papers on advanced methodologies in genetic engineering, including CRISPR/Cas technologies, gene therapy, and synthetic biology applications. - Cellular Responses to Environmental Stressors:
Research examining how cells adapt to stressors such as oxidative stress, hypoxia, and inflammation, including signaling pathways involved. - Molecular Pathogenesis of Diseases:
Investigations into the molecular basis of diseases, including cancer, neurodegenerative disorders, and infectious diseases, with a focus on potential therapeutic targets. - Bioinformatics and Computational Biology:
Studies utilizing computational approaches to analyze biological data, including genomic, transcriptomic, and proteomic analyses.
Trending and Emerging
- CRISPR and Genome Editing Advances:
There is a significant increase in publications related to CRISPR technology, focusing on its applications in gene therapy, agricultural biotechnology, and functional genomics. - Non-Coding RNAs and Their Functions:
Research on non-coding RNAs, particularly long non-coding RNAs (lncRNAs) and microRNAs, is gaining traction due to their roles in gene regulation and disease mechanisms. - Cancer Biology and Therapeutic Targets:
An increasing number of studies are investigating molecular mechanisms underlying cancer progression, with a focus on identifying novel therapeutic targets and biomarkers. - Microbiome Research:
There is a growing interest in the role of the microbiome in health and disease, with studies exploring its molecular interactions and implications for personalized medicine. - Synthetic Biology and Metabolic Engineering:
Emerging research in synthetic biology aims to design and construct new biological parts and systems, focusing on applications in medicine, agriculture, and biofuels. - Systems Biology Approaches:
The integration of systems biology approaches, which combine experimental and computational methods to understand complex biological systems, is increasingly prevalent.
Declining or Waning
- Traditional Virology Studies:
There has been a noticeable decrease in papers focused solely on classical virology, as the field has shifted towards more integrated approaches that combine virology with molecular biology and genetics. - Basic Biochemical Pathway Studies:
Research that merely describes biochemical pathways without linking them to broader biological implications or disease contexts seems to be less prevalent. - Single-Cell Analysis Techniques:
Although single-cell analysis remains important, there has been a shift towards bulk analysis methods in some studies, possibly due to the increasing complexity and cost of single-cell technologies. - Plant Molecular Biology:
Research focusing exclusively on plant molecular biology has seen a decline, with more emphasis now placed on translational applications and crop improvement through genetic engineering.
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