Cancer Discovery

Scope & Guideline

Catalyzing Collaboration for a Cancer-Free Future

Introduction

Immerse yourself in the scholarly insights of Cancer Discovery with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN2159-8274
PublisherAMER ASSOC CANCER RESEARCH
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2011 to 2024
AbbreviationCANCER DISCOV / Cancer Discov.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404

Aims and Scopes

Cancer Discovery is dedicated to advancing knowledge in the field of cancer research, with a particular focus on hematologic malignancies. The journal emphasizes the integration of basic and translational research, aiming to bridge the gap between laboratory findings and clinical applications. Its core areas include the exploration of genetic, molecular, and immunological aspects of cancer, particularly in blood cancers.
  1. Hematological Malignancies Research:
    The journal publishes significant findings related to various blood cancers, such as leukemia, lymphoma, and myeloma, focusing on their underlying biology, treatment strategies, and clinical outcomes.
  2. Innovative Therapeutic Approaches:
    A strong emphasis is placed on novel therapeutic modalities, including CAR T-cell therapy, bispecific antibodies, and immune checkpoint inhibitors, exploring their mechanisms, efficacy, and associated toxicities.
  3. Molecular and Genetic Insights:
    Research on the molecular and genetic underpinnings of cancer, including mutations, epigenetic changes, and clonal evolution, informs the understanding of disease progression and therapeutic resistance.
  4. Translational Research:
    The journal aims to translate laboratory discoveries into clinical practice, facilitating the development of personalized medicine strategies and improving patient outcomes.
  5. Collaboration and Network Building:
    It fosters collaboration among researchers, clinicians, and institutions to enhance the impact of cancer research and improve treatment paradigms.
Recent publications in Cancer Discovery reveal several emerging themes that are gaining traction within the field. These trends reflect the ongoing evolution of cancer research, particularly in hematological malignancies.
  1. CAR T-cell Therapy Innovations:
    Research related to CAR T-cell therapy is expanding, highlighting novel approaches to enhance efficacy and reduce resistance, as well as addressing complications such as neurotoxicity and immune escape.
  2. Precision Medicine and Genomic Profiling:
    There is an increasing emphasis on precision medicine, with studies focusing on genomic profiling to identify therapeutic vulnerabilities and inform personalized treatment strategies for patients.
  3. Immune Microenvironment Interactions:
    The role of the immune microenvironment in cancer progression and therapy response is a growing area of interest, investigating how immune cells and tumor interactions influence disease outcomes.
  4. Clonal Hematopoiesis and Disease Progression:
    Research on clonal hematopoiesis and its implications for cancer risk and treatment responses is on the rise, indicating a deeper understanding of its role in hematologic malignancies.
  5. Integration of Single-Cell Technologies:
    The application of single-cell sequencing and analysis techniques is emerging as a key methodology, providing insights into tumor heterogeneity and immune responses at an unprecedented resolution.

Declining or Waning

While Cancer Discovery continues to thrive in many areas, certain themes appear to be declining in prominence. This may reflect shifts in research focus or advancements in understanding that have rendered some topics less critical in current discourse.
  1. Traditional Chemotherapy Studies:
    With the rise of targeted therapies and immunotherapies, traditional studies focused solely on chemotherapy regimens are being published less frequently, indicating a shift towards more innovative treatment strategies.
  2. General Cancer Biology:
    Broad studies on cancer biology without a specific focus on hematological malignancies are becoming less common, as researchers increasingly concentrate on more specialized and relevant topics.
  3. In vitro Models of Cancer:
    There is a noticeable decrease in publications utilizing traditional in vitro models, as researchers are moving towards more sophisticated models, such as patient-derived xenografts and organoids, which provide better insights into human disease.

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