CLINICAL IMMUNOLOGY

Scope & Guideline

Exploring the Depths of Immune Responses

Introduction

Welcome to the CLINICAL IMMUNOLOGY information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of CLINICAL IMMUNOLOGY, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN1521-6616
PublisherACADEMIC PRESS INC ELSEVIER SCIENCE
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1999 to 2024
AbbreviationCLIN IMMUNOL / Clin. Immunol.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address525 B ST, STE 1900, SAN DIEGO, CA 92101-4495

Aims and Scopes

The journal "Clinical Immunology" focuses on advancing the understanding of the immune system, its disorders, and the intricate relationship between immunity and various diseases. It encompasses a wide range of research areas that contribute to the field of clinical immunology, emphasizing the need for interdisciplinary approaches in addressing complex immune-related conditions.
  1. Autoimmunity and Immune Dysregulation:
    Research on the mechanisms underlying autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, and other immune dysregulatory disorders. This includes studies on the genetic, epigenetic, and environmental factors influencing autoimmunity.
  2. Primary Immunodeficiencies:
    Exploration of the genetic basis, clinical presentations, and therapeutic approaches for various inborn errors of immunity. This includes studies on novel mutations, their implications for diagnosis and treatment, and the development of clinical guidelines.
  3. Translational Immunology:
    Integration of basic immunological research with clinical applications, including the development of novel immunotherapies, vaccine responses, and therapeutic strategies for managing immune-related diseases.
  4. Immuno-oncology:
    Investigation of the immune system's role in cancer, including the mechanisms of immune evasion by tumors, the development of immunotherapies, and the identification of biomarkers predictive of treatment response.
  5. Infectious Diseases and Immunity:
    Studies focusing on the immune response to infectious agents, including the impact of viral infections (like SARS-CoV-2) on immune function and the role of vaccination in enhancing immunity.
  6. Immunometabolism:
    Research into the metabolic pathways that influence immune cell function and the implications of metabolic dysregulation in autoimmune and inflammatory diseases.
  7. Biomarkers and Diagnostics:
    Development and validation of biomarkers for disease activity, prognosis, and treatment response in various immunological disorders.
  8. Clinical Trials and Therapeutics:
    Reporting on clinical trials investigating new therapeutic agents, including monoclonal antibodies, small molecules, and cellular therapies aimed at modulating immune responses.
The journal has seen a rise in interest in several key areas, reflecting the evolving landscape of clinical immunology and the need to address emerging challenges in immunity and disease management.
  1. COVID-19 and Immune Response:
    The pandemic has spurred a significant increase in research focused on the immune response to SARS-CoV-2, including studies on vaccine efficacy, post-viral syndromes, and the role of the immune system in disease severity.
  2. Precision Medicine in Immunology:
    An emerging focus on personalized approaches to immunotherapy and treatment for autoimmune diseases, with an emphasis on genetic and biomarker-based stratification of patients.
  3. Long COVID and Immune Dysfunction:
    Investigations into the long-term immune consequences of COVID-19, including persistent immune dysregulation and its clinical implications, have gained traction in recent publications.
  4. Neuroimmunology:
    Increased exploration of the interplay between the nervous system and immune responses, particularly in the context of autoimmune neurological disorders and neurodegenerative diseases.
  5. Microbiome and Immunity:
    Research on the relationship between the microbiome and immune system function is emerging, with studies exploring how microbiota composition influences autoimmune diseases and treatment responses.
  6. Immunotherapy Advancements:
    A growing trend in the exploration of novel immunotherapies, including bispecific antibodies, CAR-T cell therapies, and other innovative strategies targeting immune checkpoints.

Declining or Waning

Despite the journal's broad focus, certain themes have experienced a decline in frequency or prominence over recent years. This waning interest may reflect shifts in research priorities or advancements in understanding that have rendered certain topics less critical.
  1. Traditional Vaccine Research:
    Research focused solely on the efficacy and safety of traditional vaccines has decreased, likely due to the rapid development and deployment of mRNA vaccines and other novel platforms that have overshadowed conventional approaches.
  2. Single Disease Focus Studies:
    There has been a noticeable reduction in studies that concentrate exclusively on single disease models without considering the broader immunological context or comorbidities, reflecting a shift towards more integrative and holistic research approaches.
  3. Basic Immunology Without Clinical Relevance:
    Papers that present basic immunological findings without clear clinical implications have become less frequent, as the journal increasingly prioritizes studies with direct applications to patient care and treatment strategies.
  4. Historical Perspectives on Immunology:
    The publication of historical reviews or retrospective studies on immunology has waned, likely as the field moves towards more contemporary and forward-looking research that addresses current challenges.

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