Frontiers in Cellular Neuroscience
Scope & Guideline
Illuminating the cellular pathways of the brain.
Introduction
Aims and Scopes
- Neuronal and Glial Interactions:
The journal emphasizes the study of interactions between neurons and glial cells, investigating how these relationships affect brain function and contribute to neurological diseases. - Synaptic Plasticity and Function:
Research on the mechanisms underlying synaptic transmission and plasticity is a core focus, exploring how changes in synaptic function can influence behavior and cognition. - Neuroinflammation and Neurodegeneration:
The journal addresses the role of neuroinflammation in neurodegenerative diseases, examining how inflammatory processes contribute to neuronal damage and dysfunction. - Stem Cell and Regenerative Therapies:
There is a strong emphasis on the application of stem cell biology in neuroregeneration, including studies on the differentiation of neural progenitor cells and the potential of stem cell therapies for treating neurological disorders. - Modeling and Experimental Techniques:
Frontiers in Cellular Neuroscience encourages the use of advanced experimental techniques, including in vitro models, imaging technologies, and computational approaches, to study cellular mechanisms in the nervous system. - Neurodevelopment and Plasticity:
The journal covers research on the developmental aspects of the nervous system, focusing on how early-life experiences and genetic factors influence neurodevelopment and plasticity.
Trending and Emerging
- Neuroinflammation Mechanisms:
There is an increasing focus on understanding the mechanisms of neuroinflammation and its role in various neurological disorders, including Alzheimer's disease and multiple sclerosis. - Microglial Function and Diversity:
Research on the diverse roles of microglia in health and disease, including their involvement in synaptic plasticity and neuroinflammation, is rapidly evolving and attracting significant attention. - Neurovascular Unit Interactions:
Studies exploring the interactions within the neurovascular unit, including endothelial cells, astrocytes, and pericytes, are emerging as critical for understanding brain health and pathology. - Organoid Models for Disease Modeling:
The use of organoid models derived from human pluripotent stem cells to study neurodevelopment and neurodegeneration is becoming a prominent area of research. - Epigenetic Regulation in Neurobiology:
There is a growing interest in the role of epigenetic modifications in neuronal function and plasticity, particularly in the context of neurodevelopmental and neurodegenerative disorders. - Therapeutic Applications of Cannabinoids:
Research into the therapeutic potential of cannabinoids and their mechanisms of action in neurological conditions is gaining momentum as a novel area of exploration.
Declining or Waning
- Traditional Neurotransmitter Studies:
Research focusing solely on traditional neurotransmitter systems (e.g., dopamine, serotonin) without integrating newer findings on neuropeptides and glial signaling is becoming less common. - Historical Approaches to Neurodegenerative Diseases:
Studies that primarily revisit historical hypotheses regarding neurodegeneration without incorporating novel molecular and genetic insights are less frequently published. - Basic Electrophysiological Techniques:
While still important, there is a noticeable decline in studies employing basic electrophysiological techniques alone, as more sophisticated imaging and molecular approaches gain traction. - Single-Cell Analysis of Non-Neuronal Cells:
Research specifically limited to the characterization of non-neuronal cells without addressing their functional roles in neuroplasticity or disease mechanisms is becoming less prevalent. - Animal Models of Neuropsychiatric Disorders:
The reliance on traditional animal models for studying neuropsychiatric disorders, without considering the integration of human-derived models or organoids, seems to be declining.
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