CELL PROLIFERATION
Scope & Guideline
Advancing the Frontiers of Cellular Research
Introduction
Aims and Scopes
- Cancer Biology:
Research on the molecular and cellular mechanisms underlying cancer proliferation, metastasis, and resistance to therapy, including studies on tumor microenvironment interactions and novel therapeutic targets. - Stem Cell Research:
Exploration of stem cell biology, differentiation, and applications in regenerative medicine, including studies on induced pluripotent stem cells and adult progenitor cells. - Cell Signaling Pathways:
Investigations into the various signaling pathways that regulate cell proliferation, apoptosis, and differentiation, including the roles of growth factors, cytokines, and genetic modifications. - Cellular Mechanisms of Disease:
Studies examining the cellular mechanisms behind diseases such as neurodegeneration, cardiovascular diseases, and metabolic disorders, focusing on how alterations in cell function contribute to disease pathology. - Tissue Engineering and Regenerative Medicine:
Research on the development of biomaterials and cellular therapies aimed at repairing or regenerating damaged tissues and organs, including the use of 3D bioprinting and stem cell-derived products.
Trending and Emerging
- Tetrahedral Framework Nucleic Acids and Nanotechnology:
Emerging research on tetrahedral framework nucleic acids (tFNAs) and their applications in drug delivery and gene therapy is gaining momentum, reflecting a broader trend towards nanotechnology in biomedical research. - Single-Cell Sequencing and Personalized Medicine:
The increasing application of single-cell RNA sequencing technologies is enabling deeper insights into cellular heterogeneity in various diseases, particularly in cancer, enhancing the potential for personalized medicine. - Mechanisms of Regulated Cell Death:
Research focused on different forms of regulated cell death such as ferroptosis and pyroptosis is trending, highlighting their roles in cancer therapy and tissue homeostasis. - Microbiome and Immune Interactions:
Studies exploring the interactions between the microbiome, immune system, and their influence on various diseases, particularly in cancer and metabolic disorders, are emerging as a significant area of interest. - Epigenetics and Gene Regulation:
An increasing emphasis on epigenetic modifications and their roles in gene regulation, development, and disease progression reflects a growing recognition of their importance in cell proliferation and differentiation.
Declining or Waning
- Basic Mechanisms of Cell Cycle Regulation:
Research directly focused on the fundamental mechanisms of the cell cycle, while still relevant, has seen a decrease in the number of dedicated studies, potentially overshadowed by more complex interactions in cancer and stem cell contexts. - Traditional Cancer Therapies:
There is a noticeable decline in studies solely centered on traditional cancer therapies (such as chemotherapy) without innovative approaches or combinations, as the field shifts towards personalized and targeted therapies. - In vitro Models of Disease:
While in vitro models remain crucial, the focus has shifted towards more complex systems such as organoids and 3D cultures, leading to a reduction in publications centered on traditional 2D cell culture models.
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