Function
Scope & Guideline
Advancing the frontiers of cancer research and molecular medicine.
Introduction
Aims and Scopes
- Physiological Mechanisms:
The journal focuses on the fundamental physiological mechanisms underlying various biological processes, including cardiovascular, neural, renal, and muscular functions. Research often explores how these mechanisms are influenced by genetic, environmental, and pathological factors. - Molecular and Cellular Physiology:
A significant emphasis is placed on molecular and cellular physiology, investigating how cellular functions and signaling pathways contribute to overall physiological outcomes. This includes studies on ion channels, receptors, and cellular metabolism. - Translational Research:
The journal aims to bridge basic physiological research with clinical implications, highlighting studies that translate findings into potential therapeutic applications for diseases such as diabetes, hypertension, and neurodegenerative disorders. - Systems Physiology:
Research published in 'Function' often employs systems-level approaches to understand how various physiological systems interact, emphasizing integrative physiology that considers the interplay between different organ systems. - Innovative Methodologies:
'Function' encourages the use of cutting-edge techniques, including high-throughput imaging, single-cell analysis, and computational modeling, to investigate physiological questions and enhance experimental rigor.
Trending and Emerging
- Neurophysiology and Behavior:
There is an increasing focus on the relationship between neurophysiology and behavioral outcomes, particularly how neural mechanisms drive physiological responses and adaptations, as seen in studies linking neural signaling to metabolic and cognitive functions. - Exercise Physiology and Adaptation:
Research exploring the physiological adaptations to exercise is gaining traction, particularly in understanding how different forms of physical activity influence systemic health and disease prevention. - Cellular Stress Responses:
Studies investigating cellular responses to stressors, such as hypoxia or metabolic disturbances, are becoming more common. This trend reflects a broader interest in how cells adapt to physiological challenges and the implications for health. - Microbiome and Metabolism:
The interplay between the microbiome and host metabolism is emerging as a significant area of research, with studies examining how gut microbiota influence systemic physiological processes and disease states. - Precision Medicine and Personalized Physiology:
The journal is increasingly publishing research that emphasizes precision medicine approaches, exploring how individualized physiological responses can inform treatment strategies and enhance therapeutic outcomes.
Declining or Waning
- Basic Biochemistry:
Research focused solely on basic biochemical pathways without direct physiological relevance has become less prominent. There is a noticeable trend towards studies that integrate biochemical findings with physiological implications. - Historical Perspectives:
Papers that primarily focus on historical perspectives or critiques of past research methodologies appear to be waning. The journal seems to favor empirical studies with direct experimental outcomes over retrospective analyses. - Single-Factor Studies:
Investigations that examine single factors in isolation, such as specific ion channels or receptors without considering systemic interactions, are less frequently published. The journal's recent emphasis is on integrative studies that account for multiple factors influencing physiological functions.
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