CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Scope & Guideline
Fostering Global Dialogue in Life Sciences
Introduction
Aims and Scopes
- Cellular Mechanisms of Disease:
Research often addresses the cellular and molecular pathways involved in various diseases, focusing on how disruptions in these pathways lead to pathophysiological conditions. - Biochemical Signaling Pathways:
The journal publishes studies that explore specific biochemical signaling pathways, such as NF-κB, MAPK, and PI3K/Akt, which play critical roles in cell survival, proliferation, and apoptosis. - Role of Non-Coding RNAs:
A significant focus is placed on the role of non-coding RNAs, including microRNAs and long non-coding RNAs, in regulating gene expression and their implications in cancer and other diseases. - Oxidative Stress and Inflammation:
Many articles examine the effects of oxidative stress and inflammatory responses on cellular health, providing insights into therapeutic targets for various conditions. - Translational Research:
The journal highlights research that bridges basic science and clinical applications, including investigations into potential therapeutic strategies for diseases such as cancer, diabetes, and cardiovascular disorders.
Trending and Emerging
- Cancer Biology and Therapeutics:
There is a marked increase in research related to cancer biology, particularly studies investigating the molecular mechanisms underpinning tumor progression and metastasis, and how these can be targeted therapeutically. - Microbiome and Metabolism:
Emerging studies are increasingly focusing on the interplay between the microbiome and host metabolic processes, highlighting its implications for health and disease. - Cellular Stress Responses:
Research on cellular responses to stressors, including oxidative stress and nutrient deprivation, is gaining traction, emphasizing their roles in aging and disease. - Gene Editing and Functional Genomics:
With advancements in CRISPR and other gene-editing technologies, there is a growing number of publications exploring functional genomics and the potential for therapeutic applications. - Immunology and Inflammation:
The journal is seeing a rise in studies examining the immune response in various contexts, particularly how inflammation influences disease progression and treatment outcomes.
Declining or Waning
- Traditional Pharmacological Studies:
There has been a noticeable decrease in studies solely focused on traditional pharmacological approaches, as the field moves towards more integrated and mechanistic approaches to drug action. - Basic Cellular Models:
Research utilizing basic cellular models without significant translational implications appears to be waning, as there is a growing emphasis on studies that incorporate more complex in vivo systems. - Isolated Biochemical Pathway Studies:
Publications that focus narrowly on isolated biochemical pathways in vitro, without context of their roles in broader physiological or pathological processes, are becoming less common.
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