INFECTION GENETICS AND EVOLUTION
Scope & Guideline
Transforming Understanding of Pathogen-Host Interactions
Introduction
Aims and Scopes
- Genomic Epidemiology:
Research that employs genomic techniques to trace the transmission dynamics and evolutionary patterns of infectious diseases, helping to inform public health responses. - Antimicrobial Resistance:
Studies investigating the genetic basis of antimicrobial resistance in various pathogens, including bacteria and viruses, addressing the global health threat posed by resistant strains. - Phylogenetic Analysis:
Utilization of phylogenetic methods to study the evolutionary relationships among pathogens, aiding in the identification of transmission pathways and potential zoonotic sources. - Pathogen Genomics:
Comprehensive genomic analyses of pathogens to understand their genetic diversity, virulence factors, and host interactions, contributing to vaccine and therapeutic development. - Zoonotic Disease Research:
Explorations of the genetic factors that facilitate the transmission of diseases from animals to humans, focusing on the evolutionary adaptations of pathogens in various hosts. - Vaccine Development and Evaluation:
Research dedicated to the identification of novel vaccine candidates through genomic and immunoinformatic approaches, aiming to enhance vaccine efficacy against infectious diseases. - Microbiome Studies:
Investigations into the role of host-associated microbiomes in influencing infection outcomes and pathogen dynamics, providing insights into host-pathogen interactions.
Trending and Emerging
- Metagenomics and Environmental Pathogen Studies:
There is a growing interest in metagenomic approaches to study environmental and zoonotic pathogens, reflecting the need to understand the complex interactions within ecosystems and their impact on human health. - COVID-19 Research:
Following the global pandemic, there has been a significant uptick in studies related to SARS-CoV-2, focusing on its genetic variants, transmission dynamics, and implications for public health and vaccine development. - Host-Pathogen Interactions:
Emerging research is increasingly focused on the genetic and molecular interactions between hosts and pathogens, providing insights into disease susceptibility and resistance mechanisms. - CRISPR and Genome Editing Technologies:
The application of CRISPR and other genome editing technologies in infectious disease research is on the rise, highlighting innovative strategies for pathogen control and vaccine development. - Antimicrobial Stewardship and Resistance Mechanisms:
There is heightened emphasis on understanding the genetic mechanisms behind antimicrobial resistance, particularly in the context of clinical isolates, to inform stewardship practices and treatment guidelines. - Genomic Surveillance and Public Health:
The trend towards using genomic surveillance as a tool for monitoring infectious diseases and informing public health responses is increasingly prominent, particularly in tracking outbreaks and understanding pathogen evolution.
Declining or Waning
- Traditional Diagnostic Methods:
There is a noticeable reduction in studies focusing on conventional diagnostic techniques, as the field shifts towards molecular and genomic methodologies that offer greater sensitivity and specificity. - Epidemiological Studies without Genetic Component:
Research articles that solely focus on epidemiological data without integrating genetic analysis are becoming less frequent, indicating a shift towards more comprehensive studies that incorporate genetic insights. - Single-Pathogen Focus Studies:
Research that examines individual pathogens in isolation is declining, with a growing preference for studies that consider multi-pathogen interactions and the broader ecological context of infectious diseases. - Basic Virology and Bacteriology:
The journal has seen fewer articles centered on classical virology and bacteriology, as the emphasis has moved towards molecular genetics and evolutionary studies that provide deeper insights into pathogen behavior.
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