INFECTION AND IMMUNITY
Scope & Guideline
Transforming Knowledge into Public Health Solutions
Introduction
Aims and Scopes
- Microbial Pathogenesis:
The journal publishes research on various pathogens, including bacteria, viruses, fungi, and parasites, detailing their mechanisms of infection and the host responses they provoke. - Host Immune Response:
A key focus is on understanding how the immune system recognizes and responds to infections, including studies on innate and adaptive immunity, immune evasion strategies employed by pathogens, and the role of immune cells. - Vaccine Development and Therapeutics:
Research articles often cover advancements in vaccine development, including novel vaccine candidates and immunization strategies, as well as therapeutic interventions that aim to enhance host defenses against pathogens. - Microbiome and Infection Interactions:
The journal explores the interactions between the host microbiome and infectious agents, investigating how these relationships influence disease susceptibility, progression, and immune responses. - Pathogen-Host Interactions:
Studies focusing on the molecular interactions between pathogens and host cells are prevalent, including the identification of virulence factors and their roles in disease.
Trending and Emerging
- Host-Microbe Interactions:
There is a growing emphasis on understanding the dynamic interactions between host cells and microbial pathogens, including how these interactions influence disease outcomes and therapeutic responses. - Immunomodulation and Immune Evasion Strategies:
Research focusing on how pathogens manipulate host immune responses to establish infection and avoid detection is increasingly prevalent, shedding light on potential therapeutic targets. - Microbiome Influence on Infection:
The role of the microbiome in modulating host susceptibility to infections and influencing treatment outcomes is a rapidly expanding area of research, reflecting the importance of microbial communities in health and disease. - Novel Vaccine Platforms and Strategies:
Innovations in vaccine technology, including mRNA vaccines and nanoparticle-based delivery systems, are becoming more common, reflecting a shift towards more effective and versatile immunization approaches. - Inflammation and Immune Pathology:
Studies exploring the dual role of inflammation in both protective immunity and tissue damage during infections have gained prominence, emphasizing the need for a balanced immune response.
Declining or Waning
- Antibiotic Resistance Mechanisms:
While antibiotic resistance remains a significant concern, the specific mechanisms of resistance have been extensively studied, leading to fewer novel investigations in this area as researchers shift towards exploring alternative therapeutic strategies. - Single-Pathogen Studies:
There is a noticeable decrease in studies focusing solely on single pathogens. Instead, research is increasingly directed towards understanding polymicrobial infections and the interactions between different pathogens. - Basic Epidemiological Studies:
The prevalence of basic epidemiological studies has waned as researchers focus more on mechanistic insights and translational research that bridges laboratory findings with clinical applications. - In Vitro Models of Infection:
Research utilizing traditional in vitro models is declining in favor of more complex in vivo models that better mimic human disease conditions and host-pathogen interactions.
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