Immune Network
Scope & Guideline
Fostering Collaboration in Immunology and Allergy
Introduction
Aims and Scopes
- Innate and Adaptive Immunity:
The journal extensively covers research related to both innate and adaptive immune mechanisms, including the roles of various immune cells such as T cells, B cells, macrophages, and natural killer cells in health and disease. - Immunotherapy and Vaccine Development:
A significant focus is placed on the development and optimization of immunotherapies and vaccines, addressing how immune responses can be harnessed or modulated to treat diseases such as cancer and infectious diseases. - Autoimmunity and Inflammation:
Research examining the mechanisms of autoimmune diseases and chronic inflammation is a core area, with studies exploring the roles of cytokines, immune cell interactions, and signaling pathways. - Host-Pathogen Interactions:
The journal includes studies on host-pathogen interactions, particularly regarding how pathogens evade immune responses, as well as the immune system's mechanisms to combat infections. - Translational Research and Clinical Applications:
There is a consistent emphasis on translating basic immunological research into clinical applications, including the study of immune responses in various patient populations and the evaluation of new therapeutic strategies.
Trending and Emerging
- Microbiome and Immune Interactions:
Research exploring the relationship between the microbiome and immune responses is gaining traction, emphasizing how gut microbiota can influence systemic immunity and disease outcomes. - Cellular Metabolism in Immunity:
There is a rising interest in the role of cellular metabolism in shaping immune cell function, particularly how metabolic pathways affect T cell differentiation and macrophage polarization. - Long-COVID and Immune Dysregulation:
Emerging studies are increasingly focused on the immunological aspects of long-COVID, investigating how SARS-CoV-2 infection can lead to persistent immune dysregulation. - Novel Immunotherapeutic Approaches:
The exploration of novel immunotherapeutic strategies, including bispecific antibodies and cell therapies, is becoming a prominent focus, reflecting a shift towards more personalized medicine in immunotherapy. - Innate Immunity in Cancer Therapy:
There is a growing body of research investigating the roles of innate immune components, such as natural killer cells and macrophages, in the context of cancer therapy, indicating a trend towards harnessing innate immunity.
Declining or Waning
- Traditional Vaccine Platforms:
Research focused on traditional vaccine platforms, such as inactivated or live-attenuated vaccines, appears to be declining as newer mRNA and viral vector technologies gain prominence. - Basic Mechanisms of T Cell Activation:
While still important, the basic mechanisms of T cell activation have received less attention compared to more complex and context-dependent studies of T cell functions in disease settings. - Cytokine Research in Isolation:
Studies examining the roles of individual cytokines in isolation are waning, as there is a shift towards understanding the broader networks of cytokine interactions and their implications in immune responses. - Animal Models of Disease:
There has been a gradual decrease in publications focused solely on animal models of diseases, with a growing preference for studies that incorporate human data or translational approaches.
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