Journal of Cancer
Scope & Guideline
Championing open access to vital cancer research.
Introduction
Aims and Scopes
- Cancer Biology and Mechanisms:
Research exploring the cellular and molecular mechanisms underlying cancer development, progression, and metastasis. This includes studies on signaling pathways, genetic mutations, and the tumor microenvironment. - Clinical Oncology and Therapeutics:
Investigations into the efficacy and safety of cancer treatments, including chemotherapy, immunotherapy, and targeted therapies. This encompasses clinical trials and pharmacogenomic studies aimed at optimizing treatment protocols. - Epidemiology and Prevention:
Studies focused on cancer risk factors, prevention strategies, and the impact of lifestyle on cancer incidence and outcomes. This includes population-based research and analyses of health disparities. - Biomarkers and Diagnostics:
Research aimed at identifying and validating biomarkers for cancer detection, prognosis, and treatment response. This covers liquid biopsies, imaging techniques, and molecular profiling. - Patient Care and Survivorship:
Exploration of the psychosocial aspects of cancer care, including patient-reported outcomes, quality of life, and survivorship issues. This area emphasizes the importance of holistic care in cancer management. - Translational Research:
Studies bridging laboratory findings with clinical applications, focusing on how discoveries in cancer biology can lead to practical advancements in treatment and patient care.
Trending and Emerging
- Immunotherapy and Immune Microenvironment:
A significant increase in research examining the role of the immune system in cancer treatment, particularly studies exploring the efficacy of immunotherapies and the characterization of tumor-infiltrating lymphocytes. - Liquid Biopsy Technologies:
Growing interest in liquid biopsy techniques for cancer detection, monitoring, and treatment response assessment. This includes research on circulating tumor DNA and exosomal markers. - Personalized Medicine and Genomics:
A trend towards personalized cancer treatment approaches based on genomic profiling and molecular characterization of tumors. This includes studies exploring biomarkers for treatment selection. - AI and Machine Learning in Oncology:
Increasing incorporation of artificial intelligence and machine learning methodologies in cancer research, particularly for diagnostics, treatment prediction, and patient stratification. - Metabolism and Cancer:
Emerging investigations into the metabolic pathways involved in cancer progression and treatment resistance, highlighting the importance of metabolic reprogramming in tumor biology.
Declining or Waning
- Basic Science without Clinical Relevance:
There has been a noticeable decline in studies that focus solely on basic cancer biology without a clear clinical application or translational aspect. This suggests a growing preference for research that can directly inform clinical practice. - Single-Agent Therapies:
Research focused exclusively on single-agent therapies has become less common, as there is a shift towards combination therapies and personalized medicine approaches in cancer treatment. - Historical Cohort Studies:
While still relevant, traditional cohort studies that do not incorporate modern technologies (like genomics or AI) appear to be less frequent, indicating a trend towards more innovative methodologies. - Non-Targeted Prevention Strategies:
There seems to be a decline in studies centered on non-targeted prevention strategies, such as general lifestyle modifications, as the focus shifts to more personalized prevention approaches based on genetic and molecular profiling.
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