JOURNAL OF CLINICAL INVESTIGATION

Scope & Guideline

Driving discovery and dialogue in clinical medicine.

Introduction

Welcome to the JOURNAL OF CLINICAL INVESTIGATION information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of JOURNAL OF CLINICAL INVESTIGATION, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0021-9738
PublisherAMER SOC CLINICAL INVESTIGATION INC
Support Open AccessYes
CountryUnited States
TypeJournal
Convergefrom 1945 to 2024
AbbreviationJ CLIN INVEST / J. Clin. Invest.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address2015 MANCHESTER RD, ANN ARBOR, MI 48104

Aims and Scopes

The Journal of Clinical Investigation focuses on the intersection of clinical and translational research, aiming to bridge the gap between laboratory findings and clinical practice. It encompasses a wide range of topics related to human health and disease, emphasizing innovative methodologies and approaches to enhance understanding and treatment of various medical conditions.
  1. Clinical Research and Trials:
    The journal emphasizes the importance of clinical trials and research methodologies that advance patient care and treatment outcomes, particularly in cardiology, oncology, and chronic diseases.
  2. Translational Medicine:
    Research translating basic science discoveries into clinical applications is a core focus, aiming to improve diagnostic and therapeutic strategies in various health conditions.
  3. Metabolic and Cardiovascular Health:
    The journal frequently publishes studies related to metabolic syndromes, cardiovascular diseases, and their interrelations with other health conditions, highlighting the importance of lifestyle and genetic factors.
  4. Immune Response and Inflammation:
    Research on immune mechanisms, inflammation, and their roles in disease processes, including autoimmune diseases and responses to infections, is a significant area of interest.
  5. Biomarkers and Diagnostics:
    The exploration of biomarkers for disease diagnosis, prognosis, and treatment response is a key theme, with a focus on innovative diagnostic techniques and technologies.
  6. Patient-Centric Approaches:
    The journal promotes studies that prioritize patient perspectives, outcomes, and quality of life, emphasizing shared decision-making and individualized treatment plans.
The Journal of Clinical Investigation has recently highlighted several emerging themes and trends, reflecting the evolving landscape of clinical research and healthcare priorities. These themes indicate a shift towards more integrative, multidisciplinary approaches in medical research.
  1. Long COVID and Post-Acute Sequelae:
    The investigation into long-term effects of COVID-19 on health, including cardiovascular and neurological impacts, has become a significant area of research, reflecting the ongoing global health crisis.
  2. Artificial Intelligence in Medicine:
    The integration of artificial intelligence and machine learning technologies in clinical research and diagnostic tools is increasingly prevalent, indicating a trend towards data-driven approaches in healthcare.
  3. Microbiome and Metabolic Health:
    Research exploring the role of gut microbiota in metabolic disorders and their implications for diseases such as diabetes and obesity is gaining traction, highlighting the importance of the microbiome in overall health.
  4. Personalized and Precision Medicine:
    There is a notable trend towards personalized medicine approaches that consider individual genetic, environmental, and lifestyle factors in treatment strategies, enhancing patient care.
  5. Telemedicine and Remote Patient Monitoring:
    The rise of telemedicine and remote monitoring technologies, especially in the context of ongoing health crises, reflects a growing emphasis on accessibility and patient engagement in healthcare.
  6. Immunotherapy and Cancer Research:
    Innovations in immunotherapy, particularly for various cancers and autoimmune diseases, are emerging as a key focus, with studies investigating novel therapeutic targets and mechanisms.

Declining or Waning

While the Journal of Clinical Investigation maintains a robust focus on various clinical and translational topics, certain areas of research appear to be less frequently addressed over recent years. These waning scopes may reflect shifts in research priorities or emerging trends in medical science.
  1. Traditional Pharmacology Studies:
    Research centered solely on traditional pharmacological approaches without integrating new technologies or personalized medicine strategies has seen a decline, as the focus shifts towards individualized treatment plans.
  2. Basic Science Without Clinical Relevance:
    Studies that do not bridge the gap between basic science and clinical application are becoming less prominent, as the journal prioritizes research that demonstrates clear implications for patient care.
  3. Single-Condition Focus Studies:
    Research focusing exclusively on single diseases without considering comorbidities or holistic approaches to patient health is gradually declining, reflecting a broader understanding of health as interconnected.
  4. Non-Translational Studies:
    There is a waning interest in studies that do not aim to translate findings into clinical practice, as the journal increasingly values research that contributes directly to improving patient outcomes.

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