JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Scope & Guideline

Unlocking Innovations in Drug Discovery

Introduction

Immerse yourself in the scholarly insights of JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN1475-6366
PublisherTAYLOR & FRANCIS LTD
Support Open AccessYes
CountryUnited Kingdom
TypeJournal
Convergefrom 1985 to 1996, from 1998 to 1999, from 2002 to 2024
AbbreviationJ ENZYM INHIB MED CH / J. Enzym. Inhib. Med. Chem.
Frequency1 issue/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND

Aims and Scopes

The Journal of Enzyme Inhibition and Medicinal Chemistry primarily focuses on the discovery and development of enzyme inhibitors and their medicinal applications. The journal emphasizes the integration of synthetic chemistry, biological evaluation, and computational methods to advance drug discovery and therapeutic strategies.
  1. Enzyme Inhibition Research:
    The journal publishes articles that explore the mechanisms, efficacy, and selectivity of various enzyme inhibitors, focusing on their potential therapeutic applications in diseases such as cancer, diabetes, and infectious diseases.
  2. Medicinal Chemistry:
    Papers often highlight the design, synthesis, and biological evaluation of novel compounds that act as enzyme inhibitors, showcasing the intersection of chemistry and biological efficacy.
  3. Computational Drug Design and Molecular Modelling:
    The journal features studies that utilize computational methods, such as molecular docking and dynamics simulations, to predict the efficacy and selectivity of enzyme inhibitors, aiding in the rational design of new drugs.
  4. Natural Products and Derivatives:
    Research on natural compounds and their derivatives as enzyme inhibitors is prominently featured, emphasizing the exploration of traditional medicine and natural sources for novel therapeutic agents.
  5. Targeted and Multi-targeted Therapeutics:
    The journal explores the development of multi-targeted inhibitors that can simultaneously modulate multiple pathways, reflecting a growing trend in personalized medicine and complex disease treatment.
The Journal of Enzyme Inhibition and Medicinal Chemistry has identified several emerging trends reflecting the evolving landscape of enzyme inhibition research and medicinal chemistry.
  1. COVID-19 Therapeutics:
    There has been a significant increase in research focused on developing inhibitors targeting SARS-CoV-2, particularly through enzyme inhibition strategies, reflecting the urgency and relevance of this global health crisis.
  2. Dual and Multi-target Inhibitors:
    The trend towards discovering compounds that can inhibit multiple targets simultaneously is gaining momentum, as researchers seek to create more effective treatments that can address complex disease mechanisms.
  3. Artificial Intelligence and Machine Learning in Drug Discovery:
    Increasingly, studies are incorporating AI and machine learning techniques to enhance drug discovery processes, particularly in predicting the interactions and efficacy of enzyme inhibitors.
  4. Personalized Medicine Approaches:
    Research is increasingly focusing on tailoring therapies to individual patients' profiles, particularly in cancer treatment, which has led to a rise in studies on personalized enzyme inhibitors.
  5. Sustainable and Green Chemistry Practices:
    There is a growing emphasis on sustainable practices in the synthesis of enzyme inhibitors, including the use of environmentally friendly solvents and methodologies, reflecting wider trends in the scientific community towards sustainability.

Declining or Waning

While the journal continues to focus on a range of topics within enzyme inhibition and medicinal chemistry, certain themes have seen a decline in prominence or frequency in recent publications.
  1. Traditional Medicinal Approaches:
    Research focusing solely on traditional medicinal compounds without extensive modification or synthetic approaches appears to be declining, as more emphasis is placed on novel synthetic pathways and targeted therapies.
  2. Single-target Inhibitors:
    The trend towards developing inhibitors that target single enzymes is waning, with a noticeable shift towards multi-target inhibitors and combination therapies that address the complexity of diseases.
  3. Basic Mechanistic Studies:
    Although foundational studies on enzyme mechanisms remain important, there is less emphasis on purely mechanistic studies without therapeutic implications, as the journal increasingly prioritizes translational research.

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