JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
Scope & Guideline
Connecting Research to Real-World Applications
Introduction
Aims and Scopes
- Population Pharmacokinetics and Pharmacodynamics:
The journal emphasizes studies that utilize population pharmacokinetic and pharmacodynamic models to analyze drug behavior in diverse patient populations. This area is crucial for optimizing dosing regimens and understanding variability in drug responses. - Quantitative Systems Pharmacology (QSP):
QSP is a core focus, integrating biological systems modeling with pharmacokinetic and pharmacodynamic principles. This approach aids in predicting drug effects and interactions within complex biological systems, facilitating better drug development strategies. - Mechanistic and Semi-Mechanistic Modeling:
Research that develops mechanistic or semi-mechanistic models to describe drug action and interactions at various biological levels is prevalent. These models help elucidate the underlying biological processes affecting drug behavior. - Innovative Computational Techniques:
The journal showcases the application of advanced computational techniques, including machine learning and artificial intelligence, to pharmacokinetic and pharmacodynamic modeling, aiming to improve predictive accuracy and model efficiency. - Clinical Applications and Translational Research:
There is a strong emphasis on studies that bridge the gap between theoretical modeling and clinical application, particularly in areas such as oncology, rare diseases, and chronic conditions, enhancing the relevance of pharmacometric research to real-world clinical scenarios.
Trending and Emerging
- Integration of Machine Learning in Pharmacometrics:
There is a growing trend in utilizing machine learning techniques to enhance pharmacometric modeling. This includes applications in model selection, optimization, and predictive analytics, which are increasingly recognized for their potential to improve the robustness and efficiency of pharmacokinetic/pharmacodynamic analyses. - Focus on Rare Diseases and Pediatric Populations:
Research addressing pharmacokinetics and pharmacodynamics in rare diseases and pediatric populations is gaining momentum. This reflects a broader recognition of the need for tailored therapeutic strategies in these vulnerable groups. - Virtual Patient Models and Simulations:
The use of virtual patient models and simulations to predict drug responses and optimize treatment regimens is on the rise. These models allow for the exploration of various dosing scenarios and patient characteristics, enhancing translational research efforts. - Mechanistic Insights into Drug Action:
There is an increasing emphasis on studies that provide mechanistic insights into drug action and interactions, particularly through the development of semi-mechanistic and mechanistic models. This trend supports a deeper understanding of how drugs exert their effects at the biological level. - Emphasis on Quantitative Systems Pharmacology (QSP):
QSP is becoming a dominant theme, with a focus on integrating biological data with pharmacometric models to enhance the predictive capabilities of drug development processes. This approach is critical for improving the translation of preclinical findings to clinical outcomes.
Declining or Waning
- Traditional Compartmental Models:
There has been a noticeable decrease in the publication of studies exclusively relying on traditional compartmental models. As more sophisticated modeling approaches, such as physiologically-based pharmacokinetic (PBPK) models, gain traction, the relevance of simpler compartmental methods appears to be waning. - Basic Pharmacokinetic Studies:
Research focused solely on basic pharmacokinetic parameters without integrating pharmacodynamic aspects or clinical implications has decreased. The journal is increasingly favoring studies that combine pharmacokinetics with pharmacodynamics to provide a more comprehensive analysis. - Single-Agent Drug Studies:
The focus on studies examining the pharmacokinetics and pharmacodynamics of single-agent drugs is declining, as there is a growing interest in combination therapies and their complex interactions, particularly in oncology and chronic disease treatment. - Static Modeling Approaches:
Static models that do not account for variability or dynamic changes in drug effects over time are being replaced by more dynamic and flexible modeling approaches. This trend indicates a shift towards methods that better capture the complexities of drug action in real-world scenarios.
Similar Journals
DRUG DEVELOPMENT RESEARCH
Pioneering insights in pharmacology and toxicology.DRUG DEVELOPMENT RESEARCH is a premier interdisciplinary journal published by Wiley, focusing on the latest advancements in drug discovery, pharmacology, and toxicology. With an ISSN of 0272-4391 and an E-ISSN of 1098-2299, this esteemed publication has been a cornerstone in the field since its inception in 1981 and continues to provide cutting-edge research until 2024. Its rigorous peer-review process and strategic placement in Q2 of the Drug Discovery category, as well as ranking #60 out of 157 in Scopus, underscore the journal's relevance and influence, boasting a respectable 62nd percentile ranking. While the journal does not currently offer open access, it remains a vital resource for researchers, professionals, and students seeking to expand their knowledge on the processes of drug development, identifying new therapeutic targets, and assessing the efficacy and safety of novel compounds. Situated in Hoboken, NJ, this journal stands at the forefront of pharmaceutical innovation, making significant contributions to the advancement of medical science.
Drug Design Development and Therapy
Advancing Therapeutic Innovations for a Healthier TomorrowDrug Design Development and Therapy is a premier open-access journal published by DOVE MEDICAL PRESS LTD, dedicated to advancing the fields of drug discovery, pharmaceutical science, and pharmacology. With an impressive Q1 ranking in its categories as of 2023, this journal is recognized for its significant contributions to the understanding of drug design and therapeutic innovations, making it an invaluable resource for researchers, professionals, and students alike. Established in 2007 and committed to open-access since 2008, the journal provides an inclusive platform for disseminating high-quality research from around the globe. With a robust impact factor and remarkable Scopus rankings, including a 24th place in Pharmaceutical Science and a 48th place in Pharmacology, it reflects a strong percentile performance, ensuring that published articles reach and impact a wide audience. By fostering the exchange of cutting-edge information on drug development and delivery systems, Drug Design Development and Therapy continues to play a crucial role in the ongoing battle against disease, promoting innovative approaches to therapeutic solutions and enhancing patient care.
THERAPEUTIC DRUG MONITORING
Pioneering the Future of Therapeutic Drug ManagementTHERAPEUTIC DRUG MONITORING, published by Lippincott Williams & Wilkins, is a prestigious journal that focuses on the critical area of pharmacology, with a specific emphasis on the therapeutic optimization of drug therapy. With an ISSN of 0163-4356 and an E-ISSN of 1536-3694, this peer-reviewed journal has been contributing valuable research and insights to the field since its inception in 1979. As of 2023, it holds a Q2 classification in the Pharmacology category, indicating its prominent role in advancing pharmaceutical sciences. The journal aims to enhance understanding of drug effectiveness and safety through rigorous studies on drug monitoring and individualized therapy, making it an essential resource for researchers, healthcare professionals, and students dedicated to improving patient care. With its solid standing reflected in Scopus rankings, including a rank of #103 in medical pharmacology and a 62nd percentile, THERAPEUTIC DRUG MONITORING continues to be a vital publication for those aiming to contribute to and stay informed about the latest developments in the field.
Drug Research
Bridging Science and Medicine for Better OutcomesDrug Research, published by GEORG THIEME VERLAG KG, is a pivotal journal housed in the vibrant realm of pharmacology and drug discovery. With a commitment to advancing the understanding of medicinal substances, this journal serves as an essential resource for researchers, professionals, and students dedicated to the field. The journal boasts an ISSN of 2194-9379 and an E-ISSN of 2194-9387, reflecting its dual commitment to print and digital accessibility. Despite its status as a Q3 journal in both Drug Discovery and Miscellaneous Medicine categories as of 2023, it continues to offer valuable insights with a focus on the latest innovations, methodologies, and findings in drug research. Based in Germany, Drug Research promotes scholarly communication and collaboration within the scientific community, ensuring that its contributions remain impactful in shaping future therapeutic discoveries. The journal is indexed in relevant databases, enhancing its visibility and reach, thus fostering a robust academic dialogue.
XENOBIOTICA
Connecting Research with Real-World Implications.XENOBIOTICA is a premier journal in the field of pharmacology and toxicology, published by Taylor & Francis Ltd. With an ISSN of 0049-8254 and E-ISSN 1366-5928, this journal has been at the forefront of research since 1971, providing critical insights and advancements up until 2024. It is recognized for its rigorous peer-reviewed content, occupying a third quartile ranking across various categories including Biochemistry, Health, Toxicology, and Pharmacology as of 2023. The journal serves as a pivotal platform for disseminating innovative findings that address the impact of xenobiotics on health and the environment, making it an essential resource for researchers, professionals, and students engaged in these multidisciplinary fields. While it does not currently offer open access, it is widely respected for its contribution to science, evidenced by its Scopus rankings across different areas of study. The journal encourages submissions that push the boundaries of knowledge and transform our understanding of the effects of chemical substances on living organisms.
Expert Review of Clinical Pharmacology
Pioneering research that shapes the future of clinical pharmacology.Expert Review of Clinical Pharmacology, published by TAYLOR & FRANCIS LTD, is a leading peer-reviewed journal dedicated to the field of clinical pharmacology, with a strong focus on the development and application of pharmacological therapies in patient care. Boasting an impressive impact, the journal ranks in the first quartile across multiple categories including Medicine (miscellaneous), Pharmacology (medical), and Pharmacology, Toxicology and Pharmaceutics (miscellaneous), reflecting its influential position within the scientific community. With a Scopus ranking of #6 in General Pharmacology, Toxicology and Pharmaceutics, the journal also achieves a commendable 93rd percentile, further emphasizing its importance as a resource for researchers and clinicians alike. As it continues to publish innovative reviews and research articles from 2008 until 2024, the Expert Review of Clinical Pharmacology plays an essential role in advancing knowledge, improving clinical practice, and fostering collaboration among experts in pharmacology, thereby driving forward the field's evolution towards better patient outcomes.
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Fostering Excellence in Biomedical and Pharmaceutical DiscourseBIOLOGICAL & PHARMACEUTICAL BULLETIN, published by the PHARMACEUTICAL SOC JAPAN, is a prominent peer-reviewed journal that serves the fields of medicine, pharmaceutical science, and pharmacology. With an ISSN of 0918-6158 and an E-ISSN of 1347-5215, this publication has been crucial in disseminating innovative research since its inception in 1993, and it continues to contribute significantly to the body of knowledge as it converges towards 2024. Despite being classified as a non-open access journal, it maintains a respectable Q3 ranking in Medicine (miscellaneous) and Q2 in Pharmaceutical Science, highlighting its critical role in advancing scientific discourse in these areas. With Scopus rankings placing it in the 51st percentile for Pharmaceutical Science and 38th percentile for Pharmacology, BIOLOGICAL & PHARMACEUTICAL BULLETIN is an essential resource for researchers, professionals, and students looking to stay abreast of cutting-edge developments and trends in biomedicine and drug development.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
Transforming Animal Health: Where Research Meets TherapeuticsJOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS is a crucial publication in the field of veterinary medicine, dedicated to advancing knowledge and practices related to pharmacology and therapeutic interventions in animals. Published by WILEY, this peer-reviewed journal has been a reliable source of innovative research since its inception in 1978, and it continues to play an integral role in shaping veterinary pharmacology through its commitment to high-quality scientific discourse. With an impact factor reflective of its robust academic standing, the journal is categorized in the Q3 quartile for Pharmacology and Q2 for Veterinary (miscellaneous) as of 2023, highlighting its relevance and significance within these domains. It is indexed in Scopus with commendable rankings, particularly in General Veterinary, where it ranks #45 out of 194, placing it in the 77th percentile. This journal not only offers a platform for original research articles but also caters to the dissemination of practical applications and reviews that are essential for veterinarians, researchers, and students alike in enhancing animal health and welfare. Although not an open-access publication, its contributions remain accessible to those engaged in the veterinary sciences through institutional subscriptions. The journal's enduring legacy and forward-looking approach make it a vital resource for anyone interested in veterinary therapeutics and pharmacology.
CURRENT OPINION IN PHARMACOLOGY
Transforming Ideas into Impactful SolutionsCurrent Opinion in Pharmacology, an esteemed journal published by Elsevier Science Ltd, encompasses the vital field of pharmacology and drug discovery. With a solid impact factor and recognized as a Q1 journal in both Drug Discovery and Pharmacology categories for 2023, it serves as a premier platform for researchers and professionals to share innovative insights, discuss emerging trends, and explore the complexities of drug development and therapeutic applications. Established in 2001 and running through 2024, this journal provides a critical overview of advances in the field, aiming to inform and inspire the next generation of pharmacological research. Despite lacking Open Access options, it maintains a high standard of scholarly excellence, ensuring that the content remains impactful and relevant to its readers. The journal is based in the Netherlands, representing a key contributor to the academic landscape in pharmacology.
BRITISH JOURNAL OF PHARMACOLOGY
Pioneering insights into drug mechanisms and therapeutic innovations.British Journal of Pharmacology is a premier, peer-reviewed journal published by Wiley, specializing in the dynamic field of pharmacology. With a robust impact factor, this journal ranks in the top quartile (Q1) for pharmacology according to the 2023 category rankings, emphasizing its significance and reputation among the global scientific community. As an essential resource for researchers, professionals, and students alike, the journal provides a platform for innovative research spanning foundational studies to clinical applications in pharmacology, toxicology, and pharmaceutics. Since its inception in 1966, the journal has consistently contributed to the advancement of pharmacological science, fostering a deeper understanding of drug action mechanisms and therapeutic advancements. Although primarily subscription-based, the British Journal of Pharmacology is committed to disseminating high-quality research that shapes the future of the field.