JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Scope & Guideline

Unlocking the Secrets of Drug Action and Efficacy

Introduction

Welcome to the JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0022-3565
PublisherAMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1945 to 2024
AbbreviationJ PHARMACOL EXP THER / J. Pharmacol. Exp. Ther.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3995

Aims and Scopes

The Journal of Pharmacology and Experimental Therapeutics (JPET) aims to advance the understanding of pharmacological principles and experimental therapeutics through comprehensive research articles. The journal focuses on the intersection of pharmacology and therapeutics, providing a platform for innovative studies that bridge basic science and clinical applications.
  1. Pharmacological Mechanisms:
    Research exploring the mechanisms of drug action at various biological targets, including receptor interactions, signaling pathways, and metabolic processes.
  2. Therapeutic Applications:
    Studies investigating the efficacy and safety of therapeutic agents in various disease models, emphasizing clinical relevance and translational potential.
  3. Drug Development and Delivery:
    Research focused on novel drug formulations, delivery systems, and technologies aimed at improving the pharmacokinetic and pharmacodynamic profiles of therapeutics.
  4. Neuroscience and Behavior:
    Papers examining the effects of pharmacological agents on neurological function and behavior, particularly in models of pain, addiction, and neurodegenerative diseases.
  5. Toxicology and Safety Assessment:
    Studies evaluating the safety profiles of drugs and their metabolites, including toxicity mechanisms and the impact of environmental factors.
  6. Pharmacogenomics and Personalized Medicine:
    Research addressing the genetic and molecular basis of individual responses to drugs, aiming to optimize therapeutic strategies through personalized approaches.
The Journal of Pharmacology and Experimental Therapeutics is currently witnessing several emerging themes that reflect the evolving landscape of pharmacological research. These trends highlight the journal's responsiveness to contemporary challenges in therapeutics and drug development.
  1. Nanomedicine and Drug Delivery Systems:
    There is a growing trend towards the exploration of nanotechnology in drug delivery, with research focusing on enhancing the efficacy and targeting of therapeutics using nanoparticle systems.
  2. Cannabis and Cannabinoid Research:
    An increased focus on the therapeutic potential of cannabinoids in various medical conditions, including pain management and neuroprotection, is evident in recent publications.
  3. Gene Therapy and Biologics:
    Research into gene therapy, including the use of RNA-based therapeutics and monoclonal antibodies, has gained traction, reflecting advancements in biopharmaceuticals.
  4. Chronic Pain and Opioid Alternatives:
    There is a significant emphasis on identifying non-opioid alternatives for pain management, addressing the opioid crisis through innovative pharmacological strategies.
  5. Translational Pharmacology and Precision Medicine:
    Emerging studies are increasingly focusing on translational pharmacology, emphasizing the integration of pharmacogenomics to tailor therapies to individual patient profiles.
  6. Microbiome and Pharmacology:
    Research exploring the interactions between the microbiome and pharmacological agents is becoming more prominent, highlighting its implications for drug metabolism and therapeutic outcomes.

Declining or Waning

While the Journal of Pharmacology and Experimental Therapeutics continues to thrive in many areas, certain themes have been observed to decline in prominence over recent years. This could reflect shifting research priorities or emerging trends that overshadow previous areas of focus.
  1. Traditional Medicinal Approaches:
    Research focusing on classical herbal or traditional medicinal practices appears to have waned, as more emphasis is placed on molecular and mechanistic studies.
  2. Single-Agent Pharmacotherapy:
    The interest in studies solely focused on single-agent pharmacotherapy is declining in favor of combination therapies and polypharmacy approaches that consider multi-target strategies.
  3. Basic Pharmacokinetic Studies:
    There is a noticeable reduction in the publication of basic pharmacokinetic studies, with an increasing preference for more complex modeling approaches and real-world evidence.
  4. Animal Models of Drug Interaction:
    Research centered exclusively on animal models for drug-drug interactions has decreased, likely due to the emerging focus on human-based studies and advanced computational models.
  5. In vitro Studies without Clinical Relevance:
    Papers reporting in vitro findings without clear translational implications or clinical relevance are less frequently accepted, reflecting a shift towards applied research.

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