JAC-Antimicrobial Resistance
Scope & Guideline
Unraveling Mechanisms, Impacting Lives
Introduction
Aims and Scopes
- Antimicrobial Resistance Mechanisms:
Research exploring the genetic and phenotypic mechanisms underlying resistance in various pathogens, including Gram-negative and Gram-positive bacteria. - Antimicrobial Stewardship Practices:
Studies evaluating the effectiveness of antimicrobial stewardship programs across different healthcare settings, aiming to improve prescribing practices and reduce resistance. - Clinical Outcomes in Infections:
Investigations into the clinical effectiveness of various antimicrobial therapies, including novel agents and combinations, particularly in resistant infections. - Diagnostic Innovations:
Research on new diagnostic techniques for rapid identification of resistant pathogens and susceptibility testing to guide treatment decisions. - Global Perspectives on AMR:
Studies that provide insights into the burden of AMR across different regions, including low- and middle-income countries, and the impact of local practices on resistance patterns. - Public Awareness and Education:
Exploration of public knowledge and attitudes towards AMR and antibiotic use, aiming to inform educational strategies and policy interventions.
Trending and Emerging
- Genomic Surveillance of Resistance:
There is a growing emphasis on genomic studies that track the emergence and spread of resistance genes among pathogens, providing insights into transmission dynamics and potential interventions. - Innovative Therapeutic Approaches:
Research into novel antimicrobial agents and combination therapies is on the rise, particularly those targeting multidrug-resistant organisms and utilizing adjunctive therapies such as phage therapy. - AI and Machine Learning in AMR:
The integration of artificial intelligence and machine learning in predicting resistance patterns and optimizing treatment strategies is emerging as a key area of interest. - Global AMR Surveillance Initiatives:
Increased focus on global surveillance efforts to monitor AMR trends and inform public health policies, particularly in low-resource settings. - Patient-Centered Stewardship Strategies:
There is a trend towards investigating the impact of patient education and engagement on antimicrobial stewardship outcomes, aiming to enhance adherence to guidelines and reduce over-prescribing.
Declining or Waning
- Traditional Antibiotic Efficacy Studies:
There has been a noticeable decrease in studies solely focusing on the efficacy of traditional antibiotics against common pathogens, as more attention is now directed towards resistance mechanisms and novel therapies. - Single-Agent Studies:
Research focusing on the effectiveness of single-agent antibiotics is waning, with a shift towards combination therapies and innovative treatment approaches to overcome resistance. - Environmental AMR Studies:
While environmental aspects of AMR are still relevant, the frequency of publications specifically addressing environmental reservoirs of resistance has decreased in favor of clinical and translational research. - Non-Clinical Perspectives:
Previously common themes addressing the sociocultural implications of AMR and non-clinical perspectives are less prevalent, as the focus shifts towards immediate clinical applications and outcomes.
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