Medicinal Chemistry

Scope & Guideline

Catalyzing breakthroughs in drug formulation and discovery.

Introduction

Welcome to the Medicinal Chemistry information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of Medicinal Chemistry, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN1573-4064
PublisherBENTHAM SCIENCE PUBL LTD
Support Open AccessNo
CountryUnited Arab Emirates
TypeJournal
Convergefrom 2005 to 2024
AbbreviationMED CHEM / Med. Chem.
Frequency8 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES

Aims and Scopes

The journal 'Medicinal Chemistry' focuses on the exploration and development of new therapeutic agents through innovative chemical research and methodologies. It encompasses a wide range of topics relevant to drug discovery and development, aiming to bridge the gap between chemistry and pharmacology.
  1. Drug Design and Synthesis:
    The journal emphasizes the design and synthesis of new chemical entities with potential therapeutic applications, employing advanced synthetic methodologies and innovative chemical strategies.
  2. Structure-Activity Relationships (SAR):
    Research often includes detailed studies on the structure-activity relationships of compounds, aiming to optimize their pharmacological properties and efficacy.
  3. Biological Evaluation:
    Papers frequently report on the biological evaluation of newly synthesized compounds, including in vitro and in vivo studies, to assess their therapeutic potential against various diseases.
  4. Target Identification and Mechanism of Action:
    The journal covers studies that identify biological targets for new drugs and elucidate their mechanisms of action, contributing to a deeper understanding of drug efficacy.
  5. Natural Products and Derivatives:
    There is a notable interest in the modification and evaluation of natural products, exploring their potential as leads for new drug development.
  6. Interdisciplinary Approaches:
    The journal promotes interdisciplinary research that combines medicinal chemistry with molecular biology, pharmacology, and computational modeling to enhance drug discovery efforts.
The journal has shown a clear trend towards several emerging themes in medicinal chemistry research. These themes reflect the evolving landscape of drug discovery, where innovative approaches and technologies are gaining prominence.
  1. PROTACs and Targeted Protein Degradation:
    There is a growing interest in the development of PROTACs (proteolysis-targeting chimeras) as a novel strategy for targeted protein degradation, which has become a significant focus in cancer therapeutics.
  2. Nanotechnology in Drug Delivery:
    Emerging research highlights the application of nanotechnology for targeted drug delivery systems, enhancing the efficacy and reducing the side effects of therapeutic agents.
  3. Biologics and Bioconjugates:
    The rise of biologics, including monoclonal antibodies and their conjugates, is evident, with research increasingly focusing on their design, synthesis, and therapeutic applications.
  4. Antiviral Drug Development:
    In light of recent global health challenges, there has been a marked increase in research aimed at developing antiviral agents, particularly against emerging viruses like SARS-CoV-2.
  5. Artificial Intelligence in Drug Discovery:
    The integration of artificial intelligence and machine learning in drug design and discovery processes is becoming a prominent theme, facilitating faster and more efficient identification of potential drug candidates.
  6. Focus on Multi-Target Agents:
    There is an emerging trend towards the design of multi-target agents that can simultaneously address multiple pathways or mechanisms, reflecting a shift in the approach to complex diseases.

Declining or Waning

While 'Medicinal Chemistry' remains robust in many areas, certain themes appear to be declining in prevalence within the recent publications. These waning scopes may reflect shifts in research focus or emerging methodologies that overshadow previous approaches.
  1. Traditional Small Molecule Inhibitors:
    Research focusing solely on traditional small molecule inhibitors without novel modifications or innovative delivery systems seems to be less common, as the field shifts towards more complex and multifunctional agents.
  2. Single Target Drug Development:
    There is a noticeable decrease in studies centered around single-target drug development, as the trend moves towards multitargeted approaches and polypharmacology to address complex diseases.
  3. Basic Pharmacokinetic Studies:
    Papers that solely focus on basic pharmacokinetic studies without integrating them into broader drug design or therapeutic efficacy are becoming less common, signaling a shift towards more comprehensive evaluations.
  4. Conventional Synthetic Methodologies:
    The reliance on conventional synthetic methods without exploration of green chemistry or novel synthetic strategies appears to be waning, as there is increasing emphasis on sustainability and efficiency in drug synthesis.

Similar Journals

CURRENT DRUG TARGETS

Navigating the Landscape of Pharmacology
Publisher: BENTHAM SCIENCE PUBL LTDISSN: 1389-4501Frequency: 16 issues/year

CURRENT DRUG TARGETS is a leading peer-reviewed journal dedicated to advancements in the fields of Clinical Biochemistry, Drug Discovery, Molecular Medicine, and Pharmacology. Published by Bentham Science Publishers Ltd, this esteemed journal has solidified its position in the academic community with a 2023 Q2 ranking in several categories, highlighting its influence and relevance in drug research and development. With an ISSN of 1389-4501 and E-ISSN 1873-5592, CURRENT DRUG TARGETS facilitates the dissemination of high-quality articles that explore novel therapeutic strategies and drug design principles. Catered to researchers, professionals, and students, the journal has a commitment to advancing knowledge while addressing contemporary challenges in pharmacological sciences. As it converges from 2000 to 2024, CURRENT DRUG TARGETS remains a vital resource in understanding the complexities of drug action and interaction, making it indispensable for anyone pursuing cutting-edge research in related disciplines.

BIOORGANIC & MEDICINAL CHEMISTRY

Advancing the Frontiers of Biochemical Research
Publisher: PERGAMON-ELSEVIER SCIENCE LTDISSN: 0968-0896Frequency: 24 issues/year

BIOORGANIC & MEDICINAL CHEMISTRY, published by Pergamon-Elsevier Science Ltd, is a prominent journal in the fields of biochemical research and drug discovery, with an ISSN of 0968-0896 and an E-ISSN of 1464-3391. Established in 1993, it has garnered respect and recognition, evidenced by its categorization in various quartile ranks across 2023, including Q2 in Clinical Biochemistry and Pharmaceutical Science. It holds significant Scopus rankings, placing it in the 75th percentile in Pharmaceutical Science and 74th percentile in Organic Chemistry, highlighting its influential contributions to ongoing research and developments. This journal provides a platform for disseminating advancements in bioorganic and medicinal chemistry, focusing on innovative methodologies, therapeutic advancements, and molecular pharmacology. Although it does not follow an open-access model, it remains a key resource for researchers, professionals, and students aiming to stay at the forefront of scientific discovery in the UK and beyond. The journal’s commitment to enhancing knowledge within the biomedical community makes it an essential read for those passionate about this dynamic field.

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Bridging Theory and Practice in Bioorganic Science
Publisher: MAIK NAUKA/INTERPERIODICA/SPRINGERISSN: 1068-1620Frequency: 7 issues/year

Russian Journal of Bioorganic Chemistry (ISSN: 1068-1620, E-ISSN: 1608-330X), published by MAIK Nauka/Interperiodica/Springer, serves as a vital resource for researchers and professionals in the fields of bioorganic chemistry, biochemistry, and organic chemistry. With a focus on the integration of organic chemistry principles with biological processes, this journal aims to disseminate significant findings and advancements from both theoretical and practical perspectives. Although currently not open access, the journal retains a dedication to high-quality, peer-reviewed content, contributing to its reputation within the academic community. The 2023 Scopus rankings position it within the Q4 category for both biochemistry and organic chemistry, indicating its critical niche within these disciplines amid a competitive landscape. Since its inception in 1996, the journal has continued to evolve, providing enriching insights and fostering collaborations among scholars and practitioners alike, with publication converging up to the year 2024. By exploring complex biomolecular interactions and the synthesis of biologically relevant compounds, the Russian Journal of Bioorganic Chemistry remains a significant platform for advancing knowledge and innovation in the life sciences.

European Journal of Medicinal Chemistry Reports

Advancing medicinal chemistry through open access innovation.
Publisher: ELSEVIERISSN: 2772-4174Frequency: 3 issues/year

European Journal of Medicinal Chemistry Reports, published by ELSEVIER, is a vital platform dedicated to advancing the field of medicinal chemistry through open access communication of high-quality research. With an impact factor reflecting its growing influence, this journal has rapidly established a reputation for scholarly excellence since its launch in 2021. It serves as a converging point for innovative studies and reviews that span the disciplines of chemistry and molecular medicine, reflected in its Q2 and Q3 quartile rankings in relevant categories for 2023. Situated in France, the journal is accessible globally, ensuring that researchers, professionals, and students can easily engage with significant findings and methodologies in medicinal chemistry. The open access model facilitates the dissemination of knowledge, bridging gaps between laboratory research and practical applications in drug development. By fostering collaboration and highlighting emerging trends, the European Journal of Medicinal Chemistry Reports plays a crucial role in shaping the future of therapeutic innovations.

Anti-Cancer Agents in Medicinal Chemistry

Exploring the intersection of chemistry and cancer research.
Publisher: BENTHAM SCIENCE PUBL LTDISSN: 1871-5206Frequency: 10 issues/year

Anti-Cancer Agents in Medicinal Chemistry is a pivotal journal in the realm of cancer research, published by Bentham Science Publishers in the United Arab Emirates. With an ISSN of 1871-5206 and an E-ISSN of 1875-5992, this esteemed journal has been disseminating high-quality research since its inception in 2006, and is set to continue through 2024. The journal is categorized in the third quartile (Q3) across key areas including Cancer Research, Molecular Medicine, and Pharmacology, highlighting its essential role in providing valuable insights to the scientific community. Despite its open-access status being unspecified, researchers benefit from the rigorous peer-review process ensuring the publication of significant advancements. The journal ranks well within Scopus, particularly in the fields of Pharmacology and Cancer Research, which positions it as a notable resource for professionals, students, and researchers aiming to deepen their knowledge in anti-cancer strategies. Through its comprehensive scope, the journal aims to bridge the gap between medicinal chemistry and clinical applications, making it an indispensable tool for those dedicated to advancing cancer therapeutics.

ACS Medicinal Chemistry Letters

Empowering drug discovery with cutting-edge insights.
Publisher: AMER CHEMICAL SOCISSN: 1948-5875Frequency: 12 issues/year

ACS Medicinal Chemistry Letters, published by the American Chemical Society, is a distinguished journal dedicated to advancing the field of medicinal chemistry. With impressive rankings in the 2023 category quartiles—Q1 in Drug Discovery and Organic Chemistry as well as Q2 in Biochemistry—this journal serves as a vital platform for researchers seeking to publish innovative findings and methodologies in drug development and therapeutic advancements. The journal's notable impact is reflected in its Scopus rankings, where it stands at #43 in Organic Chemistry and #45 in Drug Discovery. Although it does not currently offer open access, the contributions published from 2010 to 2024 provide a wealth of knowledge critical to both academia and industry. As a key resource for students, professionals, and researchers in the fields of chemistry and pharmacology, ACS Medicinal Chemistry Letters plays an essential role in shaping the future of medicinal therapeutics.

Research Journal of Pharmacognosy

Innovating drug discovery through the lens of pharmacognosy.
Publisher: IRANIAN SOC PHARMACOGNOSYISSN: 2345-4458Frequency: 4 issues/year

Research Journal of Pharmacognosy, published by the Iranian Society of Pharmacognosy, is a pioneering forum for the dissemination of research in the field of pharmacognosy and its related disciplines. Founded in 2014 as an Open Access journal, it aims to provide swift and free access to high-quality research articles, fostering collaboration and innovation among researchers, professionals, and students. Operating from Tehran, Iran, this journal addresses a wide range of topics including complementary and alternative medicine, drug discovery, and organic chemistry, making it an invaluable resource for those researching the extraction, characterization, and application of naturally derived compounds. The journal holds a Category Quartile ranking of Q3 in Complementary and Alternative Medicine and Q4 in both Drug Discovery and Organic Chemistry for the year 2023, which underscores its growing influence within the scientific community. By serving as a platform for current advances and thought leadership in pharmacognosy, the Research Journal of Pharmacognosy plays a crucial role in bridging the gap between traditional practices and modern pharmacological applications.

PHARMACEUTICAL CHEMISTRY JOURNAL

Shaping the Future of Pharmaceutical Research.
Publisher: SPRINGERISSN: 0091-150XFrequency: 12 issues/year

Pharmaceutical Chemistry Journal is a pivotal publication in the field of pharmaceutical sciences, renowned for its in-depth articles and research findings. Published by Springer in the United States, this journal provides a crucial platform for researchers, students, and professionals dedicated to advancing drug discovery and pharmacology. With an ISSN of 0091-150X and an E-ISSN of 1573-9031, this journal has consistently aimed to promote scholarly communication and innovation within its scope since its inception in 1967. Despite its current Category Quartiles ranking of Q4 in both Drug Discovery and Pharmacology, the journal remains a valuable resource for disseminating new ideas and findings that contribute to the scientific community. Researchers benefit from the journal's commitment to high-quality peer-reviewed content, even in an environment where open access options are currently not available. As the field evolves, the Pharmaceutical Chemistry Journal continues to play an important role in shaping future advancements in drug development and safety.

DRUG AND CHEMICAL TOXICOLOGY

Innovating research for a healthier tomorrow.
Publisher: TAYLOR & FRANCIS LTDISSN: 0148-0545Frequency: 6 issues/year

Drug and Chemical Toxicology is a well-respected journal in the fields of toxicology, pharmacology, and public health, published by Taylor & Francis Ltd. Since its inception in 1978, this journal has diligently explored the effects and mechanisms of chemical exposures on health and the environment, fulfilling a crucial role in advancing scientific understanding and safeguarding public health. The journal is indexed across prestigious databases and features an impressive array of articles categorized within the Q2 and Q3 quartiles across various categories in 2023, reflecting its significance in Chemical Health and Safety as well as Environmental and Occupational Health disciplines. With an extensive reach and a focus on interdisciplinary research, Drug and Chemical Toxicology offers a rich repository of original research, reviews, and methodological advancements, catering to a diverse audience of researchers, professionals, and students dedicated to the betterment of safety and health standards. Although not an open-access publication, its articles are widely accessible to the academic community, ensuring that critical innovations and insights are shared for the greater good.

Future Medicinal Chemistry

Connecting researchers to the future of medicine.
Publisher: Newlands Press LtdISSN: 1756-8919Frequency: 24 issues/year

Future Medicinal Chemistry is a premier journal dedicated to the rapidly evolving fields of drug discovery, pharmacology, and molecular medicine. Published by Newlands Press Ltd in the United Kingdom, this journal has garnered significant attention within the academic community, evidenced by its 2023 category rankings in Scopus, placing it in the Q2 quartile for Drug Discovery and the Q3 quartiles for both Molecular Medicine and Pharmacology. With an ISSN of 1756-8919 and an E-ISSN of 1756-8927, Future Medicinal Chemistry has been a cornerstone of scholarly discourse since its inception in 2009, continuously contributing to the advancement of knowledge and discussion in medicinal chemistry. The journal is committed to publishing high-quality, peer-reviewed research that addresses the challenges and innovations in drug development and therapeutic strategies, making it an essential resource for researchers, professionals, and students seeking to stay at the forefront of these critical fields. Engage with the latest findings and methodologies that shape the future of medicine by exploring the wealth of information offered within Future Medicinal Chemistry.