CHEMICO-BIOLOGICAL INTERACTIONS

Scope & Guideline

Advancing Understanding in Pharmacology and Toxicology

Introduction

Explore the comprehensive scope of CHEMICO-BIOLOGICAL INTERACTIONS through our detailed guidelines, including its aims and scope. Stay updated with trending and emerging topics, and delve into declining areas to understand shifts in academic interest. Our guidelines also showcase highly cited topics, featuring influential research making a significant impact. Additionally, discover the latest published papers and those with high citation counts, offering a snapshot of current scholarly conversations. Use these guidelines to explore CHEMICO-BIOLOGICAL INTERACTIONS in depth and align your research initiatives with current academic trends.
LanguageEnglish
ISSN0009-2797
PublisherELSEVIER IRELAND LTD
Support Open AccessNo
CountryIreland
TypeJournal
Convergefrom 1969 to 2024
AbbreviationCHEM-BIOL INTERACT / Chem.-Biol. Interact.
Frequency18 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE 00000, IRELAND

Aims and Scopes

CHEMICO-BIOLOGICAL INTERACTIONS focuses on the intersection of chemistry and biology, emphasizing research that explores the biochemical mechanisms underlying toxicological effects, drug interactions, and therapeutic strategies. The journal publishes studies that employ a variety of methodologies including in vitro and in vivo experiments, computational modeling, and biochemical assays to elucidate the interactions between chemical agents and biological systems.
  1. Chemical Toxicology:
    Research examining the toxic effects of various chemicals, including drugs, environmental pollutants, and natural products on biological systems and their underlying mechanisms.
  2. Pharmacokinetics and Drug Interactions:
    Studies on the metabolic pathways of drugs, their interactions with enzymes, and implications for therapeutic efficacy and safety.
  3. Cancer Biology and Therapeutics:
    Investigations into the molecular mechanisms of cancer, including the development of novel therapeutic agents and the evaluation of their efficacy against various cancer types.
  4. Nanotechnology in Medicine:
    Exploration of nanomaterials and their applications in drug delivery systems, therapeutic agents, and diagnostics.
  5. Neuropharmacology and Neurotoxicity:
    Research focusing on the effects of chemical substances on the nervous system, including neuroprotective agents and the mechanisms of neurotoxic effects.
  6. Oxidative Stress and Inflammation:
    Studies that explore the role of oxidative stress and inflammatory processes in disease pathology and the development of therapeutic interventions.
  7. Natural Products Chemistry:
    Isolation and characterization of bioactive compounds from natural sources and their potential applications in health and disease.
Recent trends in the publications of CHEMICO-BIOLOGICAL INTERACTIONS indicate a growing focus on innovative therapeutic strategies and the molecular underpinnings of disease. The following themes have emerged as particularly relevant in current research.
  1. Ferroptosis and Cell Death Mechanisms:
    Research on ferroptosis, a form of regulated cell death distinct from apoptosis, has gained momentum, with studies exploring its implications in cancer and neurodegenerative diseases.
  2. Drug Repurposing and Combination Therapies:
    There is an increasing interest in repurposing existing drugs for new therapeutic applications, particularly in oncology, as well as exploring synergistic effects of drug combinations.
  3. Role of Microbiota in Health and Disease:
    The influence of gut microbiota on health, disease mechanisms, and drug metabolism is becoming a significant area of investigation, reflecting a broader understanding of systemic interactions.
  4. Biochemical Pathways in Disease:
    Emerging research is focusing on detailed biochemical pathways involved in various diseases, particularly those linked to inflammation, oxidative stress, and metabolic disorders.
  5. Nanoparticle Applications in Drug Delivery:
    The use of nanoparticles for targeted drug delivery and their role in enhancing the bioavailability and efficacy of therapeutic agents is an area of increasing research interest.
  6. Computational Toxicology and Drug Design:
    Advancements in computational methods for predicting chemical interactions, toxicity, and drug design are trending, allowing for more efficient screening of potential therapeutic agents.

Declining or Waning

While CHEMICO-BIOLOGICAL INTERACTIONS maintains a robust focus on various chemical and biological interactions, certain themes have seen a decline in prominence over recent years. This may reflect shifting research priorities or advancements in related fields.
  1. Traditional Herbal Remedies:
    Research focusing on the efficacy of traditional herbal remedies has decreased, possibly due to a shift towards more synthetic and biotechnological approaches in drug development.
  2. Environmental Toxicology of Metals:
    While still relevant, studies specifically targeting the environmental toxicology of heavy metals have become less frequent, as the field expands to encompass broader environmental impacts and novel pollutants.
  3. Basic Mechanistic Studies:
    There appears to be a waning interest in purely mechanistic studies that do not translate into therapeutic applications, as the emphasis shifts towards translational research and clinical relevance.
  4. In Vitro Models of Disease:
    The reliance on traditional in vitro models has seen a decline, with a growing preference for more complex systems such as organ-on-a-chip technologies and 3D culture systems that better mimic in vivo conditions.

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