Multiple Sclerosis Journal
Scope & Guideline
Bridging Research and Clinical Practice in MS
Introduction
Aims and Scopes
- Clinical Management of Multiple Sclerosis:
Focuses on the latest advancements in the management and treatment of MS, including the effectiveness of disease-modifying therapies (DMTs), patient adherence, and the impact of comorbidities on treatment outcomes. - Neuroimaging and Biomarkers:
Explores the role of advanced imaging techniques and biomarkers in diagnosing and monitoring MS progression, including studies on MRI, optical coherence tomography, and serum biomarkers such as neurofilament light chain. - Pathophysiology and Immunology:
Investigates the underlying biological mechanisms of MS, including immune responses, neuroinflammation, and the role of various immune cell populations in disease progression. - Cognitive and Psychological Aspects:
Examines the cognitive impairments associated with MS, their impact on quality of life, and the effectiveness of cognitive rehabilitation strategies. - Socioeconomic and Global Health Perspectives:
Addresses the disparities in healthcare access, treatment outcomes, and the social determinants affecting individuals with MS across different populations. - Patient-Centered Research:
Emphasizes the importance of patient-reported outcomes and experiences in shaping treatment approaches and healthcare policies.
Trending and Emerging
- Digital Health and Remote Monitoring:
Research on the use of digital technologies, including telemedicine and mobile health applications, has surged as a response to the COVID-19 pandemic and the need for continuous patient monitoring. - Immunotherapy and Novel Therapeutics:
There is an increasing focus on newer immunotherapies, including BTK inhibitors and monoclonal antibodies, as well as personalized treatment approaches based on genetic and immunological profiling. - Longitudinal Studies and Real-World Evidence:
A growing emphasis on longitudinal studies and the collection of real-world data to better understand treatment effects and disease progression in diverse patient populations. - Cognitive Rehabilitation and Quality of Life:
Research targeting cognitive rehabilitation strategies and their impact on the quality of life for MS patients has gained momentum, reflecting a broader focus on patient-centered care. - Environmental and Lifestyle Factors:
An emerging interest in how lifestyle factors, including diet and physical activity, influence MS outcomes, alongside research into the gut-brain axis and microbiome interactions.
Declining or Waning
- Traditional Pharmacological Approaches:
Studies focusing on older, less effective pharmacological treatments for MS, such as first-generation DMTs, have decreased as the field moves towards more innovative therapies and personalized medicine. - Epidemiological Studies:
While important, the frequency of general epidemiological studies on MS prevalence and incidence has waned as more specific and targeted research questions have emerged. - Basic Science Research:
Research focused solely on basic science without direct clinical implications has become less prominent, as the journal increasingly prioritizes translational research that connects laboratory findings to clinical practice.
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