npj Systems Biology and Applications
Scope & Guideline
Advancing the Frontiers of Systems Biology
Introduction
Aims and Scopes
- Systems Modeling and Simulation:
The journal publishes research that develops and applies mathematical and computational models to simulate biological processes, from cellular signaling pathways to tumor microenvironments. - Quantitative Analysis of Omics Data:
A core area of focus is the integration and analysis of multi-omics data (genomics, transcriptomics, proteomics, etc.) to uncover insights into biological functions and disease mechanisms. - Biological Network Dynamics:
Research on the dynamics of biological networks, including gene regulatory networks and metabolic pathways, is a significant theme, contributing to understanding cellular behavior and interactions. - Therapeutic Development and Drug Discovery:
The journal emphasizes the use of systems biology approaches to inform drug discovery, including modeling drug responses and identifying potential therapeutic targets. - Personalized Medicine:
There is a strong focus on personalized medicine, utilizing computational tools to tailor treatments based on individual patient profiles and disease characteristics. - Synthetic Biology and Bioengineering:
The journal also covers advancements in synthetic biology, including the design of biological systems and the engineering of biomolecular interactions for therapeutic purposes.
Trending and Emerging
- Artificial Intelligence and Machine Learning in Biology:
There is an increasing trend towards using AI and machine learning techniques for data analysis, predictive modeling, and drug discovery, enhancing the ability to interpret complex biological data. - Integration of Multi-Omics Approaches:
Emerging research emphasizes the integration of various omics data types to gain comprehensive insights into biological systems, reflecting a trend towards holistic understanding of cellular functions. - Computational Immunology and Cancer Research:
A growing focus on computational approaches to immunology and cancer biology is evident, with studies exploring immune responses and therapeutic strategies using systems biology frameworks. - Dynamic Systems and Temporal Modeling:
There is an increased interest in dynamic modeling approaches that consider the temporal aspects of biological systems, particularly in relation to disease progression and treatment responses. - Synthetic Biology for Therapeutic Applications:
Research in synthetic biology is gaining momentum, particularly studies that explore the engineering of biological systems for therapeutic interventions, such as engineered T cells and biomolecular circuits.
Declining or Waning
- Traditional Experimental Biology:
There is a noticeable decrease in the publication of studies strictly focused on traditional experimental biology methods, as the emphasis has shifted towards computational and systems-based approaches. - Basic Mechanistic Studies without Systems Integration:
Research that focuses solely on basic mechanistic studies without integrating systems biology perspectives appears to be waning, as there is a growing demand for studies that connect molecular mechanisms to larger biological systems. - Single-Method Approaches:
Papers that employ single-method approaches, such as purely biochemical assays or isolated cellular studies, have seen a decline in favor of multi-disciplinary research that incorporates computational modeling and systems analysis.
Similar Journals
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Unraveling the Mysteries of Biological FunctionsBIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, published by Elsevier, serves as a pivotal journal in the fields of biochemistry and biophysics, with a long-standing history dating back to 1956. This esteemed publication, bearing the ISSN 0304-4165 and E-ISSN 1872-8006, continuously contributes to advancing our understanding of complex biological processes through rigorous research articles and reviews. It notably holds a distinguished position with a Q2 classification in Biochemistry and a Q1 ranking in Biophysics for 2023, reflecting its high relevance and impact within these scientific domains. The journal is also recognized within the Scopus metrics, taking a rank of #40 out of 152 in Biophysics and #173 out of 438 in Biochemistry, thus placing it in the 74th and 60th percentiles respectively. Academics and professionals in the life sciences will find this journal an essential resource for current research, cutting-edge techniques, and comprehensive reviews aimed at enhancing the understanding of biological functions. While BIOCHIMICA ET BIOPHYSICA ACTA is not an open-access journal, it remains a cornerstone publication for those seeking to stay at the forefront of biochemical and biophysical research.
CURRENT PROTEIN & PEPTIDE SCIENCE
Exploring the Dynamic World of Proteins and PeptidesCURRENT PROTEIN & PEPTIDE SCIENCE, published by Bentham Science Publishers, is a pivotal journal dedicated to the dynamic and rapidly evolving fields of protein and peptide research. With an ISSN of 1389-2037 and an E-ISSN of 1875-5550, this esteemed journal serves as a platform for disseminating cutting-edge findings from various disciplines, including biochemistry, cell biology, and molecular biology. Recognized for its influence with a 2023 Scopus ranking placing it within the top quartiles of its categories—Q3 in Biochemistry, Q4 in Cell Biology, and Q2 in Medicine—the journal not only enhances the visibility of critical research but also supports the academic community in advancing our understanding of the molecular foundations of life. Established in 2000 and running through 2024, CURRENT PROTEIN & PEPTIDE SCIENCE is positioned to cater to the interests of researchers, professionals, and students alike, providing them with open access to vital knowledge that fuels innovation and scientific inquiry in the United Arab Emirates and beyond.
JOURNAL OF MATHEMATICAL BIOLOGY
Exploring the Intersection of Math and Biology.Journal of Mathematical Biology, published by Springer Heidelberg, is a leading international journal dedicated to the interdisciplinary field of mathematical modeling and its applications in biology. With an ISSN of 0303-6812 and an E-ISSN of 1432-1416, this journal has established its prominence within the academic community, reflected in its impressive rankings: Q1 in Agricultural and Biological Sciences (miscellaneous) and Q2 in both Applied Mathematics and Modeling and Simulation as of 2023. Covering a broad scope from ecological modeling to biomathematics, the journal serves as a crucial platform for researchers, professionals, and students alike to disseminate innovative work that bridges the gap between theoretical mathematics and biological phenomena. The journal, which spans from its inception in 1974 to 2024, emphasizes rigorous research while ensuring a high level of scholarly communication through its selective review process. With its solid reputation, the Journal of Mathematical Biology continues to significantly contribute to advancements in mathematical sciences and their essential role in understanding complex biological systems.
COMPUTATIONAL BIOLOGY AND CHEMISTRY
Transforming Discoveries in Life Sciences with Computational ExpertiseCOMPUTATIONAL BIOLOGY AND CHEMISTRY is a distinguished academic journal published by Elsevier Science Ltd, focusing on the dynamic intersection of computational biology, biochemistry, and chemistry. With an ISSN of 1476-9271 and an E-ISSN of 1476-928X, this journal is committed to disseminating high-quality research that employs computational techniques to solve complex biological and chemical problems. As of 2023, the journal holds a substantial impact factor reflecting its significance and rigorous peer-review process, categorized in the Q2 quartile for both Computational Mathematics and Organic Chemistry, alongside Q3 classifications in Biochemistry and Structural Biology. With a continuous publication history spanning from 2003 to 2024, it serves as a critical resource for researchers, professionals, and students alike. The journal offers various open access options, ensuring that vital research findings are accessible to a global audience, further enhancing collaboration across disciplines. Engage with cutting-edge studies and contribute to the evolving landscape of computational methodologies in the life sciences through this esteemed publication.
Cell Reports Methods
Innovating Methodologies, Inspiring DiscoveriesCell Reports Methods is a cutting-edge journal published by CELL PRESS, focusing on innovative methodologies in the vast fields of biochemistry, genetics, biotechnology, and radiological sciences. Launched in 2021, it has rapidly ascended to attain a Q1 ranking across multiple disciplines in the latest 2023 metrics, reflecting its influential contribution to the scientific community. With an emphasis on practical and rigorous experimental approaches, this journal serves as a vital resource for researchers looking to advance their methodologies and collaborate on significant findings in their respective specialties. Despite not being an open-access publication, Cell Reports Methods ensures broad accessibility through institutional subscriptions, allowing researchers from various backgrounds to engage with high-quality scholarly work. The journal presents a unique platform for sharing insights from interdisciplinary methods that foster innovation and discovery, ultimately shaping the future of scientific research.
BRIEFINGS IN BIOINFORMATICS
Pioneering Insights in Computational BiologyBRIEFINGS IN BIOINFORMATICS is a premier academic journal dedicated to the dynamic field of bioinformatics, published by Oxford University Press. With a prestigious standing reflected in its Q1 quartile rankings in both Information Systems and Molecular Biology, this journal serves as an essential resource for researchers, professionals, and students eager to explore the intersection of biology and computational sciences. The journal not only publishes high-impact research articles but also reviews and critical commentaries that push the boundaries of understanding in bioinformatics. As it converges its objectives towards fostering innovation and knowledge dissemination from 2000 to 2024, BRIEFINGS IN BIOINFORMATICS offers rich insights that remain pivotal to advancements in genomic studies, data integration, and computational tools. Its ranking in the top percentiles of Scopus—30th among 394 in Computer Science and 44th among 410 in Molecular Biology—underscores the journal's influential presence in the academic community. Engaging with the latest research and trends, this journal is integral for anyone invested in the future of life sciences and data analytics.
GENERAL PHYSIOLOGY AND BIOPHYSICS
Illuminating Complex Biological InteractionsGENERAL PHYSIOLOGY AND BIOPHYSICS, published by AEPRESS SRO, is a pivotal journal in the fields of biophysics and physiology, dedicated to advancing knowledge and fostering research in these increasingly vital disciplines. Established in 1983 and set to converge in 2024, the journal provides a platform for scholarly articles that explore the intricate relationships between biological systems and physical principles. Its current category quartiles include Q3 in Biophysics and Q4 in Physiology, demonstrating a growing influence among researchers, with current Scopus ranks reflecting its commitment to quality and relevance. Despite not being an open-access publication, the journal remains a valuable resource for professionals and students aiming to stay informed on the latest discoveries and methodologies. By supporting interdisciplinary research and innovation, GENERAL PHYSIOLOGY AND BIOPHYSICS plays a crucial role in shaping the understanding of complex biological interactions and applications in medicine.
Interdisciplinary Sciences-Computational Life Sciences
Exploring the Intersection of Computation and Life SciencesInterdisciplinary Sciences-Computational Life Sciences, published by SPRINGER HEIDELBERG, is a premier journal dedicated to advancing the field of life sciences through the lens of computational methods. With an ISSN of 1913-2751 and an E-ISSN of 1867-1462, this journal serves as a significant platform for researchers and professionals alike, fostering innovation and collaboration across various disciplines. As a testament to its impact, the journal holds a Q2 category status in Biochemistry, Genetics and Molecular Biology, Computer Science Applications, and Health Informatics, reflecting its influential contributions and rigorous peer-review process. The Scopus rankings demonstrate its esteemed placement within its fields, with notable percentiles that highlight its relevance and reach. While the journal operates under a traditional access model, its commitment to publishing high-quality research continues to stimulate important discussions and developments within the scientific community. Founded in 2009 and converging through 2024, Interdisciplinary Sciences-Computational Life Sciences remains an essential resource for the latest discoveries at the intersection of computation and life sciences, appealing to both seasoned researchers and enthusiastic students eager to contribute to this dynamic field.
Current Opinion in Systems Biology
Exploring the intersections of biology, mathematics, and technology.Current Opinion in Systems Biology is an esteemed academic journal published by ELSEVIER, focusing on the dynamic and interdisciplinary field of systems biology. Since its inception in 2017, the journal has made significant strides in disseminating cutting-edge research and innovative perspectives across various domains, including applied mathematics, biochemistry, and drug discovery. With an impressive impact factor reflecting its prominent position as a Q1 journal in multiple categories—including Applied Mathematics, Biochemistry, and Computer Science Applications—it serves as a vital resource for researchers, professionals, and students alike. The journal embraces a comprehensive approach to understanding complex biological systems, fostering a deeper insight into the interactions within biological and computational frameworks. This makes it an essential conduit for advancing knowledge and innovation in systems biology, facilitating the development of new methodologies that could lead to groundbreaking discoveries.
BIOINFORMATICS
Connecting Biology and Technology for a Sustainable FutureBIOINFORMATICS, published by Oxford University Press, is a leading journal in the realms of biochemistry, computational mathematics, and computer science, with a notable impact factor that underscores its significance in the field. Since its inception in 1985 and continuing through its expected convergence in 2024, the journal has maintained a prestigious reputation, proudly residing in the Q1 category across multiple disciplines, including molecular biology and statistics. With a Scopus ranking placing it within the top percentiles of its categories, BIOINFORMATICS serves as an essential platform for disseminating high-quality research that advances knowledge and innovation at the intersection of biology and computational sciences. This journal not only offers both subscription and open access options, ensuring wider availability of its cutting-edge research, but it has also become a crucial resource for researchers, professionals, and students aiming to stay at the forefront of bioinformatics and related fields. Explore the latest findings and trends that define the future of biological research through this esteemed publication, any inquiries regarding the journal can be directed to its offices located at Great Clarendon St, Oxford OX2 6DP, England.