PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
Scope & Guideline
Advancing the Frontiers of Biochemical Knowledge
Introduction
Aims and Scopes
- Biochemical Mechanisms in Disease:
Explores the biochemical pathways and molecular interactions involved in various diseases, including cancer, neurodegenerative disorders, and metabolic syndrome. - Biophysical Techniques in Research:
Utilizes advanced biophysical methods such as spectroscopy, microscopy, and imaging techniques to investigate the structure and dynamics of biomolecules. - Therapeutic Applications and Innovations:
Focuses on the development and application of novel therapeutic strategies, including drug delivery systems, gene therapy, and immunotherapy. - Interdisciplinary Approaches:
Encourages research that integrates biochemistry, biophysics, molecular biology, and bioinformatics to address complex biological questions. - Regulatory Mechanisms in Cellular Processes:
Investigates the regulatory pathways that control cellular functions, including signal transduction, gene expression, and metabolic regulation.
Trending and Emerging
- Neurobiological Mechanisms and Mental Health:
Increased focus on understanding the neurobiological underpinnings of mental health disorders, including the role of exercise, neuroinflammation, and therapeutic interventions. - CRISPR and Gene Editing Technologies:
Growing interest in CRISPR technology and its applications in gene therapy, diagnostics, and synthetic biology, reflecting the rapid advancements in genetic research. - Nanotechnology in Medicine:
Emerging research on the use of nanomaterials for drug delivery, diagnostics, and therapeutic applications, highlighting the intersection of materials science and biomedicine. - Metabolomics and Systems Biology:
Increased exploration of metabolomic profiling and systems biology approaches to understand complex biological systems and disease mechanisms. - Immunotherapy and Cancer Treatment:
A notable rise in studies focused on immunotherapy techniques, including the development of vaccines and targeted therapies for various cancers.
Declining or Waning
- Basic Biochemical Pathways:
Research on traditional biochemical pathways, such as glycolysis or Krebs cycle, has decreased as newer, more complex interactions are being explored. - Generalized Drug Development:
There is a waning interest in broad drug development studies, with a shift towards more targeted therapies and personalized medicine. - In vitro Studies without Mechanistic Insight:
Papers focusing solely on in vitro studies without clear mechanistic insights or translational relevance are becoming less common. - Animal Models in Basic Research:
The use of traditional animal models for basic biochemical research is declining as researchers seek more innovative and humane alternatives.
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