TETRAHEDRON
Scope & Guideline
Exploring the molecular universe since 1957.
Introduction
Aims and Scopes
- Organic Synthesis:
The core focus of Tetrahedron is on organic synthesis methodologies, including the development of new synthetic routes, reactions, and strategies that enhance the efficiency and selectivity of chemical transformations. - Catalysis:
The journal showcases advancements in catalytic processes, including homogeneous and heterogeneous catalysis, with a particular emphasis on environmentally friendly and sustainable methods. - Medicinal Chemistry:
Research articles often explore the synthesis and biological evaluation of new pharmacological agents, highlighting the connection between synthetic chemistry and drug development. - Materials Science:
Tetrahedron publishes studies on the synthesis and characterization of novel materials, including polymers and nanomaterials, focusing on their applications in various fields such as electronics and biomedicine. - Theoretical and Computational Chemistry:
The journal includes computational studies that assist in understanding reaction mechanisms, predicting outcomes, and providing insights into the structure-activity relationships of synthesized compounds.
Trending and Emerging
- Sustainable Chemistry:
There is an increasing number of articles dedicated to green synthesis methods, emphasizing the development of processes that minimize environmental impact and utilize renewable resources. - Photoredox Catalysis:
The use of visible-light-mediated synthetic methodologies is gaining traction, with numerous papers exploring photoredox catalysis as a versatile tool for generating complex organic molecules. - Bioconjugation and Chemical Biology:
Research focusing on bioconjugation strategies and the synthesis of compounds with biological relevance is on the rise, reflecting a trend towards integrating organic synthesis with biological applications. - Nanomaterials and Nanocatalysis:
There is a noticeable increase in studies exploring the synthesis and application of nanomaterials in catalysis and drug delivery, highlighting their potential in addressing contemporary challenges in chemistry and medicine. - Multicomponent Reactions:
The trend towards multicomponent reactions is evident, with research highlighting their efficiency in synthesizing complex molecules in a single step, thus streamlining synthetic processes.
Declining or Waning
- Traditional Organic Reactions:
There has been a noticeable decline in the number of publications focused on classical organic reactions that do not incorporate modern advancements or applications, such as traditional nucleophilic substitutions or electrophilic additions. - Synthetic Methodologies with Limited Novelty:
Research that presents incremental advancements in well-established synthetic methodologies without significant innovation or new applications appears to be less frequent, suggesting a shift towards more novel and impactful contributions. - Isolated Natural Product Synthesis:
The synthesis of isolated natural products without a clear application or relevance to broader synthetic challenges is becoming less common, as the focus shifts towards compounds with therapeutic potential or broader implications.
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