Aging and Disease
Scope & Guideline
Unlocking the science of aging and disease.
Introduction
Aims and Scopes
- Age-Related Molecular Mechanisms:
The journal emphasizes research on the molecular and cellular mechanisms underlying aging, including studies on oxidative stress, mitochondrial dysfunction, and cellular senescence. - Chronic Diseases and Aging:
A significant focus is placed on the relationship between aging and chronic diseases such as Alzheimer's disease, cardiovascular diseases, and diabetes, exploring their pathophysiology and potential interventions. - Therapeutic Interventions and Innovations:
The journal highlights novel therapeutic approaches and interventions aimed at mitigating age-related decline, including pharmacological treatments, stem cell therapies, and lifestyle modifications. - Translational Research and Clinical Studies:
Research that bridges the gap between laboratory findings and clinical applications is a core aspect, with studies designed to inform clinical practice for aging populations. - Public Health and Aging:
The journal also addresses public health issues related to aging, including epidemiological studies, healthcare policies, and the impact of socio-environmental factors on aging.
Trending and Emerging
- Microbiome and Aging:
The relationship between the gut microbiome and aging is increasingly prominent, with studies exploring how microbiota influences age-related diseases and overall health. - Cellular Senescence and its Implications:
Research on cellular senescence, particularly its role in aging and chronic diseases, is rapidly expanding, highlighting its potential as a therapeutic target. - Neuroinflammation and Cognitive Decline:
There is a growing focus on the role of neuroinflammation in cognitive decline and neurodegenerative diseases, suggesting new avenues for intervention. - Machine Learning and AI in Aging Research:
The integration of machine learning and artificial intelligence in analyzing aging-related data is emerging as a critical area, promising to enhance predictive models and therapeutic strategies. - Interdisciplinary Approaches to Aging:
An increase in interdisciplinary studies that combine insights from genetics, epigenetics, neuroscience, and public health reflects a holistic view of aging research.
Declining or Waning
- Traditional Pharmacological Approaches:
There is a notable decrease in studies focusing solely on traditional pharmacological interventions without considering holistic or integrative approaches to aging. - Basic Animal Models:
Research utilizing basic animal models for aging studies has waned, with a shift towards more complex models that better mimic human aging and diseases. - Isolated Studies on Single Age-Related Diseases:
The journal has seen fewer publications that isolate studies on single diseases, as there is a growing trend towards understanding multi-morbidity and the interconnectedness of age-related conditions.
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