Aging-US
Scope & Guideline
Advancing Knowledge in Aging Research
Introduction
Aims and Scopes
- Molecular and Cellular Mechanisms of Aging:
Research on the underlying biological processes that contribute to aging, including cellular senescence, oxidative stress, autophagy, and epigenetic modifications. - Age-Related Diseases:
Studies focusing on various diseases associated with aging, such as Alzheimer's disease, cardiovascular diseases, cancer, and metabolic disorders, highlighting their pathophysiology and potential therapeutic interventions. - Impact of Lifestyle and Environmental Factors:
Exploration of how diet, physical activity, and environmental exposures influence aging and the onset of age-related diseases. - Innovative Therapeutic Approaches:
Development and evaluation of new therapeutic strategies, including pharmacological agents, lifestyle interventions, and regenerative medicine techniques aimed at promoting healthy aging. - Biomarkers of Aging:
Identification and validation of biomarkers that can predict biological age, disease risk, and therapeutic responses in aging populations. - Genetic and Epigenetic Influences:
Investigation into the genetic and epigenetic factors that affect aging processes and contribute to the variability in aging among individuals.
Trending and Emerging
- Longevity and Anti-Aging Interventions:
Increased focus on lifestyle interventions, dietary restrictions, and pharmacological agents that target aging processes to extend lifespan and healthspan. - Immunoaging and Inflammation:
Growing interest in how aging affects immune function and the role of inflammation in age-related diseases, leading to research on immunotherapies and anti-inflammatory strategies. - Epigenetics of Aging:
Emerging studies on how epigenetic modifications influence aging processes, with implications for biomarkers and therapeutic targets. - Microbiome and Aging:
Research exploring the relationship between gut microbiota and aging, including how microbiome composition affects health outcomes in older adults. - Artificial Intelligence in Aging Research:
Utilization of AI and machine learning techniques to analyze aging data, predict outcomes, and personalize interventions in aging populations. - Targeting Cellular Senescence:
Increased emphasis on understanding and targeting cellular senescence as a therapeutic strategy to mitigate age-related decline and diseases.
Declining or Waning
- Traditional Herbal Remedies:
Research focusing on traditional herbal treatments for aging and age-related diseases has decreased, as the field shifts towards more molecular and pharmacological approaches. - Basic Descriptive Studies:
There has been a decline in purely descriptive studies that do not incorporate mechanistic insights or translational aspects, reflecting a trend towards more hypothesis-driven research. - Non-Specific Aging Models:
The use of non-specific or generalized aging models in research is waning, with a preference for more targeted and disease-specific models that offer clearer insights into aging mechanisms.
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