CELL CYCLE

Scope & Guideline

Exploring the Dynamics of Cell Proliferation.

Introduction

Immerse yourself in the scholarly insights of CELL CYCLE with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN1538-4101
PublisherTAYLOR & FRANCIS INC
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2002 to 2024
AbbreviationCELL CYCLE / Cell Cycle
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106

Aims and Scopes

The journal 'CELL CYCLE' primarily focuses on the intricate mechanisms governing cell proliferation, division, and apoptosis, exploring their implications in cancer biology and therapeutic interventions. The journal aims to bridge basic and clinical research, highlighting novel findings that elucidate the molecular pathways involved in cell cycle regulation and related cellular processes.
  1. Cell Cycle Regulation and Mechanisms:
    Research articles frequently explore various aspects of cell cycle control, including the roles of cyclins, cyclin-dependent kinases (CDKs), and checkpoint proteins in normal and cancerous cells.
  2. Molecular Mechanisms in Cancer:
    The journal emphasizes studies that investigate the molecular underpinnings of cancer progression, metastasis, and resistance to therapies, often focusing on key signaling pathways and regulatory networks.
  3. Role of Non-Coding RNAs:
    There is a significant emphasis on the functions of long non-coding RNAs (lncRNAs) and microRNAs in regulating gene expression related to cell proliferation, differentiation, and apoptosis in various cancer types.
  4. Therapeutic Strategies and Drug Resistance:
    Papers often discuss novel therapeutic approaches, including targeted therapies and the mechanisms of drug resistance, highlighting the significance of understanding cellular responses to treatments.
  5. Cellular Stress Responses and Aging:
    Research on cellular responses to stress, senescence, and their implications in aging and age-related diseases are also core areas of focus.
Recent publications in 'CELL CYCLE' reveal emerging trends that highlight the evolving landscape of cell cycle research, particularly in the context of cancer and therapeutic development. These trends reflect a growing interest in molecular complexity and the interplay between various cellular mechanisms.
  1. Integrative Omics Approaches:
    The use of multi-omics strategies, including genomics, transcriptomics, and proteomics, is gaining traction, providing comprehensive insights into the regulation of cell cycle processes and cancer biology.
  2. Microenvironmental Influences on Cell Cycle:
    There is an increasing focus on how tumor microenvironments affect cell cycle regulation, including the role of stromal interactions and extracellular matrix components in tumor progression.
  3. CircRNA Research:
    The investigation of circular RNAs (circRNAs) as regulatory molecules in the cell cycle and cancer has emerged as a significant theme, with studies exploring their potential as biomarkers and therapeutic targets.
  4. Targeted Therapy and Immunotherapy:
    Research on targeted therapies and immunotherapies is expanding, particularly studies that elucidate how cell cycle regulation affects treatment responses and resistance mechanisms.
  5. Cellular Senescence and Aging:
    An increasing number of articles focus on the role of cellular senescence in cancer biology and aging, exploring how senescence influences tumorigenesis and response to therapy.

Declining or Waning

Over recent years, certain themes within 'CELL CYCLE' have seen a noticeable decrease in prominence. This waning interest may reflect shifting research priorities or advancements in technology that allow for more nuanced exploration of previously established topics.
  1. Basic Cell Cycle Studies:
    There has been a decline in publications focusing solely on fundamental aspects of the cell cycle without direct implications for cancer or therapeutic intervention, as more studies aim for translational relevance.
  2. Traditional Cancer Biomarkers:
    Research centered solely on established cancer biomarkers is decreasing, with a shift toward identifying novel markers and understanding their functional roles within complex regulatory networks.
  3. In vitro Models:
    There is a marked reduction in studies employing basic in vitro models for cell cycle research, as the field increasingly favors more sophisticated in vivo and multi-dimensional models that better mimic the tumor microenvironment.
  4. Single Pathway Analysis:
    The trend has shifted away from isolated studies of single signaling pathways, with more research focusing on integrative approaches that consider multiple pathways and their interactions.

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