APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
Scope & Guideline
Advancing knowledge in histology and pathology.
Introduction
Aims and Scopes
- Immunohistochemical Techniques:
The journal emphasizes the development and application of immunohistochemical methods for the diagnosis of various tumors, exploring new markers and techniques that improve diagnostic precision. - Molecular Morphology:
It investigates the relationship between molecular changes and histopathological features, aiding in understanding tumor biology and behavior. - Diagnostic and Prognostic Biomarkers:
The journal concentrates on identifying and validating biomarkers that can predict disease outcomes, therapeutic responses, and aid in the stratification of patients for personalized treatment. - Case Studies and Clinical Applications:
Through detailed case reports and studies, the journal provides practical insights into the real-world application of immunohistochemistry and molecular techniques in pathology. - Emerging Technologies:
The journal explores innovative methodologies, such as digital pathology and machine learning applications in immunohistochemistry, enhancing the field's capability for analysis and diagnosis.
Trending and Emerging
- Immune Checkpoint Analysis:
There is a growing focus on the role of immune checkpoint proteins, such as PD-L1, in cancer diagnosis and treatment, particularly in the context of immunotherapy, demonstrating the relevance of immunological factors in tumor management. - Multiplex Immunohistochemistry:
The use of multiplex techniques is gaining traction, allowing for the simultaneous detection of multiple markers, which enhances diagnostic capabilities and provides a more comprehensive understanding of tumor microenvironments. - Integration of Digital Pathology:
The incorporation of digital imaging and quantitative analysis in immunohistochemistry is emerging as a trend, facilitating more precise evaluations and standardizing assessments across laboratories. - Molecular Profiling and Genomic Studies:
Research that combines immunohistochemistry with genomic and molecular profiling is increasing, reflecting a trend towards personalized medicine and targeted therapies for cancer treatment. - Prognostic and Predictive Biomarkers:
There is an expanding emphasis on identifying biomarkers that not only predict outcomes but also guide therapeutic decisions, aligning with the shift towards personalized oncology.
Declining or Waning
- Traditional Histopathology Techniques:
There is a noticeable reduction in studies solely focused on conventional histopathological techniques without the integration of immunohistochemistry or molecular analysis, indicating a shift towards more advanced diagnostic methods. - Single Marker Studies:
Research concentrating on single immunohistochemical markers has become less frequent, as the field moves towards multi-marker panels and more comprehensive approaches to diagnosis. - General Cancer Characterization:
Publications that broadly characterize cancers without specific immunohistochemical or molecular insights have diminished, reflecting a trend towards more targeted and detailed investigations.
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