ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
Scope & Guideline
Advancing the Frontiers of Immunology and Therapy
Introduction
Aims and Scopes
- Immunological Mechanisms:
The journal extensively covers the mechanisms of immune responses, including topics like T cell function, cytokine signaling, and the role of various immune cells in disease processes. - Therapeutic Innovations:
A key focus is on experimental therapies and innovations in immunotherapy, particularly regarding conditions like cancer, autoimmune diseases, and infectious diseases. - Translational Research:
The journal emphasizes studies that bridge laboratory findings with clinical applications, aiming to translate basic immunological research into therapeutic strategies. - Pathogen-Host Interactions:
Research exploring the dynamics between pathogens and host immune responses, including studies on viral infections and autoimmune responses. - Regulatory and Tolerogenic Mechanisms:
The journal addresses how immune tolerance and regulation can impact disease progression and therapy, especially in transplantation and autoimmune disorders. - Emerging Technologies in Immunology:
The incorporation of new technologies such as genomics, proteomics, and artificial intelligence in understanding immune responses and developing therapies.
Trending and Emerging
- Cancer Immunotherapy:
An increasing number of studies focus on immunotherapeutic approaches in oncology, highlighting CAR-T cell therapy and other innovative strategies to enhance anti-tumor immunity. - Impact of Microbiome on Immunity:
Research exploring the role of gut microbiota in modulating immune responses and its implications for various diseases is gaining traction, indicating a broader interest in microbiome-immune interactions. - Artificial Intelligence in Immunology:
There is a growing interest in the application of artificial intelligence and big data analytics to understand immune responses and improve therapeutic strategies. - Vaccine Responses and Immunogenicity:
With the emergence of new pathogens, studies assessing vaccine efficacy and immune responses, especially in the context of COVID-19, are increasingly prevalent. - Personalized Medicine in Immunotherapy:
The trend towards personalized approaches in immunotherapy, including tailored treatments based on individual genetic and immunological profiles, is becoming more prominent.
Declining or Waning
- Traditional Autoimmune Disease Models:
Research using conventional autoimmune disease models appears to be waning, possibly due to a shift towards more complex and translational models that better mimic human diseases. - Single Disease Focus:
There is a noticeable decline in studies focusing solely on individual diseases, with more research now emphasizing holistic and systems biology approaches. - Basic Immunology without Clinical Relevance:
Studies that explore basic immunological principles without clear clinical implications are becoming less frequent, reflecting a trend towards research with direct therapeutic applications.
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