JOURNAL OF EXPERIMENTAL MEDICINE

Scope & Guideline

Exploring the Depths of Disease Mechanisms

Introduction

Immerse yourself in the scholarly insights of JOURNAL OF EXPERIMENTAL MEDICINE with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN0022-1007
PublisherROCKEFELLER UNIV PRESS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1896 to 1902, from 1905 to 2024
AbbreviationJ EXP MED / J. Exp. Med.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address950 THIRD AVE, 2ND FLR, NEW YORK, NY 10022

Aims and Scopes

The Journal of Experimental Medicine focuses on advancing the understanding of various aspects of immunology, cell biology, and pathology, emphasizing experimental and translational research that contributes to the field of medicine.
  1. Immunology and Immune Response:
    The journal publishes research exploring the mechanisms of immune responses, including the roles of various immune cells, cytokines, and signaling pathways in health and disease. This includes studies on T cells, B cells, innate lymphoid cells, and their interactions with pathogens.
  2. Cancer Immunotherapy:
    A significant focus is on the development and evaluation of cancer immunotherapies, including checkpoint inhibitors, CAR-T cell therapies, and vaccine strategies. Research often investigates the mechanisms of tumor immune evasion and the potential for enhancing anti-tumor immunity.
  3. Autoimmunity and Inflammation:
    The journal features studies examining the underlying mechanisms of autoimmune diseases and chronic inflammatory conditions, including the roles of autoantibodies and immune cell dysregulation.
  4. Infectious Diseases:
    Research related to the immune response to infectious agents, including viral, bacterial, and parasitic infections, is a core area. The journal emphasizes understanding host-pathogen interactions and the development of therapeutic strategies.
  5. Cellular and Molecular Mechanisms:
    Papers often delve into the cellular and molecular basis of disease, including studies on signaling pathways, gene regulation, and cellular metabolism that influence immune function and disease outcomes.
  6. Translational Medicine:
    The journal aims to bridge basic research with clinical applications, encouraging studies that translate findings from the laboratory into potential therapeutic interventions for various diseases.
Recent publications in the Journal of Experimental Medicine reflect emerging trends and themes that are gaining traction in the scientific community. These themes highlight the evolving landscape of immunology and translational medicine.
  1. Single-Cell Analysis Techniques:
    There is a notable increase in studies utilizing single-cell RNA sequencing and other single-cell technologies to dissect cellular heterogeneity within the immune system and tumors. This trend underscores the importance of understanding individual cell behaviors in complex biological systems.
  2. Personalized and Precision Medicine:
    Research focusing on personalized approaches to immunotherapy, including the identification of biomarkers for treatment response and tailoring therapies to individual patient profiles, is rapidly emerging as a significant theme.
  3. Microbiome and Immune Interactions:
    Studies exploring the relationship between the microbiome and immune system health are increasingly featured. This includes research on how gut microbiota influence immune responses and disease outcomes.
  4. Inflammation and Metabolism:
    The intersection of metabolic processes and immune function is gaining attention, with research investigating how metabolic pathways influence immune cell behavior and chronic inflammation.
  5. Therapeutic Target Identification:
    There is a growing trend towards identifying and validating novel therapeutic targets within the immune system and cancer biology, reflecting the journal's commitment to translational research.

Declining or Waning

While the Journal of Experimental Medicine continues to thrive in many research areas, some themes have seen a decline in publication frequency or focus over recent years. This can indicate shifting priorities within the field or a saturation of research in those areas.
  1. Basic Virology:
    Research focused solely on the basic virology of pathogens, without a strong emphasis on immune responses or therapeutic implications, has seen a decline. The journal increasingly favors studies that link virology with immunological outcomes.
  2. In vitro Studies Without Clinical Relevance:
    There appears to be a waning interest in in vitro studies that do not translate to in vivo or clinical contexts. The journal favors studies that provide insights into real-world applications or mechanisms in living systems.
  3. Non-immune Cell Focused Research:
    Research that primarily focuses on non-immune cells in isolation, without considering their interactions with the immune system, has become less prominent. The journal emphasizes the importance of immune cell interactions.

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