Biologics-Targets & Therapy
Scope & Guideline
Empowering Research in Gastroenterology and Beyond
Introduction
Aims and Scopes
- Biologics and Therapeutic Development:
The journal prioritizes research on biologics, including monoclonal antibodies, therapeutic proteins, and gene therapies, contributing to the development of novel treatment modalities in various diseases. - Molecular Mechanisms and Pathophysiology:
A core focus is on elucidating the molecular mechanisms underlying disease processes, particularly in cancer and autoimmune disorders, which aids in identifying potential therapeutic targets. - Clinical Applications and Case Studies:
The journal publishes clinical studies and case reports that provide insights into the real-world effectiveness and safety of biologic therapies, fostering a deeper understanding of patient management. - Innovative Therapeutic Approaches:
Research on emerging therapies, such as CRISPR/Cas9 genome editing, stem cell therapies, and novel drug delivery systems, is emphasized as a way to address unmet medical needs. - Interdisciplinary Research:
The journal encourages interdisciplinary approaches that combine biology, pharmacology, and clinical medicine to develop comprehensive strategies for disease treatment.
Trending and Emerging
- Immunotherapy and Cancer Treatment:
There is a significant increase in research related to immunotherapy, including monoclonal antibodies and CAR T-cell therapies, highlighting their transformative impact on cancer treatment. - Biologic Treatments for Autoimmune Disorders:
The journal is increasingly publishing studies on biologic therapies for autoimmune diseases, showcasing their effectiveness and safety in managing conditions like rheumatoid arthritis and ulcerative colitis. - Gene Therapy and Genome Editing:
Research on gene therapy applications and CRISPR/Cas9 genome editing is on the rise, emphasizing innovative approaches to treat genetic disorders and cancers. - Natural Products and Herbal Medicine:
There is a growing interest in the efficacy of herbal therapies and natural products as adjuncts or alternatives to conventional treatments, particularly in cancer care. - Patient-Centric Treatment Approaches:
Recent publications reflect a trend towards research that emphasizes patient adherence, treatment persistence, and quality of life improvements, aligning with the shift towards personalized medicine.
Declining or Waning
- Traditional Chemotherapy Approaches:
Research focusing on conventional chemotherapy methods has decreased, as the emphasis shifts towards targeted therapies and biologics that offer more personalized treatment options. - Basic Laboratory Studies without Clinical Relevance:
There is a noticeable decline in purely basic research studies that do not translate into clinical applications, as the journal increasingly prioritizes research with direct implications for patient care. - General Reviews on Established Therapies:
The frequency of broad, non-specific reviews on established therapies has waned, reflecting a shift towards more focused and innovative reviews that discuss recent advancements and novel treatment strategies. - Invasive Surgical Techniques:
The publication of studies centered on invasive surgical techniques has decreased, possibly due to the rising interest in minimally invasive and biologically-based therapeutic approaches. - Epidemiological Studies without Therapeutic Insights:
Epidemiological studies that do not provide insights into therapeutic interventions or biologic treatments have become less common, as the journal aims to concentrate on actionable research.
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