DRUG DISCOVERY TODAY
Scope & Guideline
Advancing the Frontiers of Drug Discovery
Introduction
Aims and Scopes
- Drug Discovery and Development Processes:
The journal covers comprehensive aspects of drug discovery, including target identification, lead discovery, optimization, and preclinical and clinical development. - Innovative Therapeutic Strategies:
It highlights novel therapeutic approaches, including small molecules, biologics, and combination therapies aimed at addressing complex diseases. - Technological Integration:
The journal emphasizes the integration of advanced technologies such as artificial intelligence, machine learning, and nanotechnology in the drug discovery process. - Regulatory Perspectives:
It discusses the regulatory challenges and frameworks that impact drug development, ensuring compliance with evolving standards in the pharmaceutical industry. - Emerging Therapeutic Targets and Modalities:
The journal explores new molecular targets and therapeutic modalities, including gene and cell therapies, immunotherapies, and precision medicine. - Interdisciplinary Collaboration:
It promotes collaboration between academia and industry to foster innovation in drug discovery, emphasizing the importance of cross-disciplinary research.
Trending and Emerging
- Artificial Intelligence in Drug Discovery:
The application of AI and machine learning in drug discovery is rapidly growing, facilitating data analysis, predictive modeling, and innovative approaches to target identification. - Nanotechnology and Nanomedicine:
There is an increasing focus on nanotechnology applications in drug delivery systems, enhancing therapeutic efficacy and reducing side effects. - Immunotherapies and Personalized Medicine:
Research on immunotherapies, especially in oncology, and personalized medicine approaches is trending, reflecting the shift towards tailored therapeutic strategies. - Gene and Cell Therapies:
Emerging interest in gene and cell therapies is notable, with advancements in CRISPR technologies and vector design for targeted therapeutic applications. - Multi-Target Strategies:
The exploration of multi-target drugs and polypharmacology is gaining traction as researchers seek to address complex diseases with multifactorial approaches. - Sustainable Drug Development:
There is a growing emphasis on environmentally sustainable practices in drug development, including greener chemistry and biodegradable materials.
Declining or Waning
- Traditional Drug Repurposing:
While drug repurposing remains a relevant strategy, the focus on traditional methods has waned as novel approaches to drug discovery gain traction. - Conventional Small Molecule Approaches:
There is a noticeable decline in papers exclusively focused on conventional small molecule drug design, with more emphasis now on biologics and combination therapies. - Single-Target Drug Development:
The exploration of single-target drugs is decreasing as the field shifts towards multi-target strategies and polypharmacology to enhance therapeutic efficacy. - Efficacy Studies without Mechanistic Insights:
There is a decline in studies that report efficacy without delving into the underlying mechanisms, as the scientific community increasingly values mechanistic understanding. - Focus on Established Therapeutics:
Research centered on established therapeutics is declining in favor of innovative and experimental approaches that address unmet medical needs.
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