CANCER BIOLOGY & THERAPY
Scope & Guideline
Advancing the frontiers of cancer research and treatment.
Introduction
Aims and Scopes
- Cancer Mechanisms and Pathways:
The journal explores underlying biological mechanisms of cancer, including genetic, epigenetic, and metabolic pathways that drive tumorigenesis and cancer progression. - Therapeutic Strategies and Innovations:
It publishes research on novel therapeutic approaches, including targeted therapies, immunotherapies, and combination treatments aimed at improving patient outcomes. - Precision Medicine and Biomarkers:
A significant focus is on precision medicine, including the identification and validation of biomarkers that can predict treatment responses and guide personalized therapy. - Tumor Microenvironment and Immunology:
Research on the tumor microenvironment, including interactions between cancer cells and immune cells, is emphasized, highlighting the role of immune evasion and therapy resistance. - Clinical Applications and Trials:
The journal also includes studies from clinical trials and real-world evidence that inform clinical practices and therapeutic decision-making in oncology.
Trending and Emerging
- Immunotherapy and Resistance Mechanisms:
Research on cancer immunotherapy, including mechanisms of resistance and strategies to enhance immune responses, has gained significant traction, reflecting the growing importance of immuno-oncology. - Molecular Targeting and Precision Medicine:
There is an increasing focus on precision medicine, with studies aimed at understanding molecular targets and the development of therapies tailored to specific genetic profiles of tumors. - Role of the Tumor Microbiome:
Emerging studies are investigating the influence of the tumor microbiome on cancer progression and treatment response, highlighting its potential role in therapeutic strategies. - Exosomes and Extracellular Vesicles:
Research into the role of exosomes and extracellular vesicles in cancer communication, metastasis, and therapy resistance has become a prominent theme, indicating a shift in understanding tumor biology. - Epigenetic Modifications:
The exploration of epigenetic changes in cancer and their implications for therapy is on the rise, suggesting a renewed interest in how these modifications affect tumor behavior and treatment responses.
Declining or Waning
- Traditional Chemotherapy Approaches:
There has been a noticeable decrease in studies solely focusing on traditional chemotherapy regimens, as the field shifts towards more targeted and personalized treatment strategies. - Basic Cell Line Studies:
Research utilizing standard cancer cell lines without additional context or innovative methodologies appears to be declining, with a trend towards more complex models that better represent tumor biology. - Single Modality Treatments:
Papers centered around single-agent therapies are becoming less common, reflecting a movement towards combination therapies and multi-modal approaches for more effective cancer treatment.
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