CARCINOGENESIS

Scope & Guideline

Exploring Innovations in Cancer Treatment and Research

Introduction

Welcome to your portal for understanding CARCINOGENESIS, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN0143-3334
PublisherOXFORD UNIV PRESS
Support Open AccessNo
CountryUnited Kingdom
TypeJournal
Convergefrom 1980 to 2024
AbbreviationCARCINOGENESIS / Carcinogenesis
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressGREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND

Aims and Scopes

CARCINOGENESIS focuses on the molecular mechanisms underlying cancer development, progression, and treatment strategies. The journal emphasizes research that integrates basic science with clinical applications, highlighting innovative methodologies and interdisciplinary approaches.
  1. Molecular Mechanisms of Carcinogenesis:
    Research exploring the cellular and molecular pathways that lead to cancer development, including genetic mutations, epigenetic changes, and signaling pathways.
  2. Cancer Biology and Microenvironment:
    Studies investigating the interactions between cancer cells and their surrounding microenvironment, including the role of tumor-associated macrophages, extracellular vesicles, and stromal cells.
  3. Preventive and Therapeutic Strategies:
    Research aimed at developing and evaluating novel preventive measures and therapeutic interventions for various cancer types, including drug efficacy and resistance mechanisms.
  4. Biomarkers and Prognostic Indicators:
    Identification and validation of biomarkers for early detection, prognosis, and treatment response in cancer patients, utilizing genomic, transcriptomic, and proteomic approaches.
  5. Environmental and Lifestyle Factors in Cancer Risk:
    Investigations into how environmental exposures, dietary habits, and lifestyle choices contribute to cancer risk and progression.
  6. Technological Innovations in Cancer Research:
    Application of advanced technologies such as machine learning, bioinformatics, and next-generation sequencing to enhance our understanding of cancer biology.
Recent publications in CARCINOGENESIS indicate several emerging themes that are gaining traction within the field. These trends reflect the evolving landscape of cancer research, with a focus on innovative approaches and interdisciplinary strategies.
  1. Cancer Immunotherapy and Microenvironment Interactions:
    There is a rising interest in understanding how the immune microenvironment influences tumor progression and response to therapy, particularly in relation to immune checkpoint inhibitors.
  2. Role of Non-Coding RNAs in Cancer:
    Research on long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) as significant regulators of cancer biology is increasingly prominent, suggesting their potential as therapeutic targets or biomarkers.
  3. Metabolic Reprogramming in Cancer:
    Studies exploring how cancer cells alter metabolic pathways to support growth and survival are on the rise, highlighting the importance of metabolism in cancer therapy.
  4. Machine Learning and AI Applications:
    The application of machine learning and artificial intelligence to predict cancer outcomes, identify new therapeutic targets, and analyze complex datasets is rapidly increasing.
  5. Personalized Medicine Approaches:
    There is a clear trend towards personalized medicine, with research focusing on tailoring treatments based on individual genetic profiles and tumor characteristics.
  6. Impact of Gut Microbiota on Cancer:
    Emerging research on the relationship between gut microbiota and cancer development or treatment response is gaining attention, indicating a shift towards understanding the host-microbe interactions.

Declining or Waning

While CARCINOGENESIS continues to publish a wide array of studies, certain themes appear to be declining in prominence based on recent publications. These waning areas may reflect shifts in research focus or emerging priorities in the field.
  1. Traditional Chemotherapy Mechanisms:
    Research focused on classical chemotherapy mechanisms and their direct effects on cancer cells is less prevalent, as newer targeted therapies and immunotherapies gain attention.
  2. Single-Agent Drug Studies:
    There is a noticeable decrease in studies solely investigating the efficacy of single-agent chemotherapeutics, with a growing preference for combination therapies and multi-target approaches.
  3. Basic Histopathological Studies:
    Traditional histopathological analyses without integrating molecular or genetic data seem to be less common, as the field moves towards more comprehensive, multi-omics studies.
  4. Animal Models of Cancer:
    While still relevant, the reliance on traditional animal models is decreasing as researchers explore alternative models, including patient-derived xenografts and organoids.
  5. General Epidemiological Studies:
    Generic epidemiological studies that do not incorporate molecular or mechanistic insights are becoming less frequent, as the emphasis shifts towards more integrative and translational research.

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