CELL BIOCHEMISTRY AND FUNCTION
Scope & Guideline
Exploring the Intricacies of Biochemical Functionality
Introduction
Aims and Scopes
- Cancer Biology and Therapeutics:
The journal frequently publishes studies that investigate the biochemical pathways involved in cancer progression and therapy, including targeted therapies, chemoresistance, and the role of non-coding RNAs. - Metabolic Disorders and Diabetes:
Research exploring the biochemical underpinnings of metabolic disorders, particularly diabetes mellitus, is a core area, with a focus on insulin signaling, cellular metabolism, and therapeutic interventions. - Stem Cell Biology and Regenerative Medicine:
The journal highlights advancements in stem cell research, including the therapeutic potential of mesenchymal stem cells and their derivatives, and the mechanisms through which they promote tissue regeneration. - Neurobiology and Neurological Disorders:
Studies on cellular mechanisms in neurological diseases, including the role of oxidative stress, inflammation, and cellular signaling pathways in neurodegeneration, are prominent. - Immunology and Inflammation:
Research addressing the biochemical aspects of immune response and inflammation is a significant focus, particularly in the context of autoimmune diseases and cancer. - Nanotechnology and Drug Delivery Systems:
The journal explores innovative drug delivery systems, including nanoparticle-based approaches, to enhance therapeutic efficacy and reduce side effects in various diseases. - Microbial and Plant-Derived Therapeutics:
Investigations of bioactive compounds from plants and microbes, their mechanisms of action, and their potential therapeutic applications are regularly featured.
Trending and Emerging
- Biochemical Mechanisms of Cancer Immunotherapy:
A surge in research examining the biochemical pathways involved in cancer immunotherapy, including immune checkpoint inhibitors and the role of the tumor microenvironment, is evident. - Role of Non-Coding RNAs in Disease Mechanisms:
There is an increasing focus on the role of long non-coding RNAs and microRNAs in regulating cellular processes related to cancer, metabolic disorders, and other diseases. - Metabolomics and Systems Biology:
Studies employing metabolomics to explore systemic biochemical changes in diseases are becoming more prevalent, reflecting an interest in holistic approaches to understanding health and disease. - Targeted and Personalized Medicine Approaches:
Research emphasizing personalized medicine, particularly in cancer treatment, through targeted therapies based on individual biochemical profiles is on the rise. - Microbiome Research in Health and Disease:
The influence of the microbiome on human health and disease, including its biochemical interactions with host metabolism and immunity, is emerging as a significant research area. - Regenerative Medicine and Tissue Engineering:
Advancements in regenerative medicine and tissue engineering, particularly related to stem cell therapies and bioengineering approaches for tissue repair, are increasingly featured.
Declining or Waning
- Traditional Pharmacology:
There is a noticeable decrease in studies focused solely on traditional pharmacological approaches without integrating modern biochemistry or molecular biology techniques. - Basic Cellular Mechanisms without Disease Context:
Research that purely investigates basic cellular mechanisms, without linking findings to specific diseases or therapeutic applications, has become less frequent. - Animal Models with Limited Relevance to Human Disease:
The use of animal models that do not adequately mimic human diseases or conditions has declined, as there is a growing preference for more relevant models that can provide insights applicable to human health. - Single-Cell Studies without Comprehensive Analysis:
While single-cell studies are gaining traction, there is a waning interest in studies that do not employ comprehensive analyses, such as integrating multi-omics approaches. - In Vitro Studies without Clinical Correlation:
Research focusing solely on in vitro experiments without correlating findings to clinical implications or outcomes has seen a decline, as there is an increasing demand for translational research.
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