MOLECULAR AND CELLULAR BIOCHEMISTRY
Scope & Guideline
Connecting Molecular Insights to Clinical Applications
Introduction
Aims and Scopes
- Molecular Mechanisms of Disease:
Investigates the biochemical pathways and molecular interactions that contribute to various diseases, including cancer, cardiovascular diseases, and metabolic disorders. - Cellular Signaling and Regulation:
Explores the cellular signaling pathways and regulatory mechanisms that influence cell behavior, including proliferation, apoptosis, and differentiation. - Biomarkers and Therapeutic Targets:
Focuses on the identification and validation of biomarkers for disease diagnosis, prognosis, and therapeutic targets, particularly in cancer and metabolic syndromes. - Stem Cell Biology and Regenerative Medicine:
Studies the role of stem cells in development and their potential therapeutic applications for tissue regeneration and repair. - Nutritional Biochemistry and Pharmacology:
Examines the impact of dietary components and pharmacological agents on cellular processes and their potential applications in disease prevention and treatment. - Emerging Technologies in Biochemistry:
Utilizes cutting-edge techniques such as CRISPR, single-cell sequencing, and metabolomics to advance understanding of biochemical processes.
Trending and Emerging
- Ferroptosis and Cell Death Mechanisms:
An increased interest in ferroptosis as a regulated form of cell death is evident, highlighting its implications in cancer, neurodegeneration, and organ injury. - MicroRNA and Non-Coding RNA Regulation:
The role of microRNAs and long non-coding RNAs in regulating gene expression and their involvement in various diseases, particularly cancer and metabolic disorders, is gaining momentum. - Metabolomics and Systems Biology:
A growing emphasis on metabolomics and systems biology approaches is seen, allowing for a comprehensive understanding of cellular metabolism and its implications in health and disease. - Immunometabolism and Inflammation:
Research focusing on the intersection of metabolism and immune response is trending, especially in the context of chronic diseases and COVID-19. - Targeted Therapies and Precision Medicine:
There is a noticeable increase in studies exploring targeted therapies and precision medicine approaches, particularly in oncology and chronic diseases. - Stem Cell-Derived Therapeutics:
Research on the therapeutic potential of stem cells and their derivatives, including exosomes, is emerging strongly, reflecting the interest in regenerative medicine.
Declining or Waning
- Classical Pharmacology Studies:
There has been a noticeable decrease in traditional pharmacological studies, likely due to the increasing shift towards personalized medicine and targeted therapies. - Basic Biochemical Pathways without Disease Context:
Research focusing solely on fundamental biochemical pathways without linking them to specific diseases or therapeutic implications is becoming less prominent. - Animal Models in Basic Research:
The reliance on animal models for basic biochemical research is declining as researchers increasingly seek alternative methods, such as organoids or in vitro models, to study disease mechanisms. - General Reviews without Novel Insights:
Reviews that do not provide new insights or advancements in the field are less frequently published, as the journal emphasizes innovative contributions.
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