Genes & Diseases

Scope & Guideline

Exploring the molecular pathways of health and illness.

Introduction

Immerse yourself in the scholarly insights of Genes & Diseases with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN2352-4820
PublisherKEAI PUBLISHING LTD
Support Open AccessYes
CountryChina
TypeJournal
Convergefrom 2014 to 2024
AbbreviationGENES DIS / Genes Dis.
Frequency6 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address16 DONGHUANGCHENGGEN NORTH ST, Building 5, Room 411, BEIJING, DONGCHENG DISTRICT 100009, PEOPLES R CHINA

Aims and Scopes

The journal 'Genes & Diseases' focuses on the intersection of genetics and various diseases, emphasizing the molecular mechanisms underlying disease pathology and potential therapeutic interventions. It provides a platform for innovative research that integrates genomics, molecular biology, and clinical applications.
  1. Molecular Genetics and Disease Mechanisms:
    Research exploring the genetic basis of diseases, including the identification of mutations, polymorphisms, and their roles in disease progression.
  2. Transcriptional and Epigenetic Regulation:
    Studies on how transcriptional control and epigenetic modifications influence gene expression in the context of various diseases.
  3. Cancer Biology and Therapeutics:
    Investigations into the molecular mechanisms of cancer, including tumor microenvironment interactions, signaling pathways, and therapeutic targets.
  4. Immunology and Autoimmunity:
    Research on immune responses in disease states, including the role of immune checkpoints, inflammatory pathways, and autoimmune conditions.
  5. Stem Cell Biology and Regenerative Medicine:
    Exploration of stem cell mechanisms, differentiation, and their therapeutic applications in disease treatment and tissue regeneration.
  6. Metabolism and Disease:
    Studies on metabolic pathways and their alterations in diseases such as obesity, diabetes, and cancer, focusing on therapeutic implications.
  7. Neurobiology and Neurodegenerative Diseases:
    Research into the genetic and molecular underpinnings of neurodegenerative diseases, including Alzheimer's and Parkinson's disease.
  8. Infectious Diseases and Host Response:
    Investigations into the genetic factors affecting susceptibility to infectious diseases and the host's immune response mechanisms.
The journal 'Genes & Diseases' has been at the forefront of exploring new and innovative research themes. Recent publications indicate a significant shift towards several trending and emerging scopes that reflect the current landscape of biomedical research.
  1. Multi-Omics Approaches:
    There is a growing emphasis on integrating genomic, transcriptomic, proteomic, and metabolomic data to provide a comprehensive understanding of disease mechanisms and therapeutic targets.
  2. Precision Medicine and Personalized Therapies:
    Research focused on tailoring treatment strategies based on genetic and molecular profiling of patients is gaining traction, reflecting the shift towards individualized healthcare.
  3. Ferroptosis and Regulated Cell Death:
    Ferroptosis, a form of regulated cell death, is emerging as a significant area of research, particularly in its implications for cancer therapy and neurodegenerative diseases.
  4. Immunotherapy and Cancer Microenvironment:
    Studies exploring the interactions between cancer cells and the immune microenvironment, including the role of immune checkpoints and tumor-infiltrating lymphocytes, are increasingly prominent.
  5. Gene Editing Technologies:
    The application and implications of CRISPR and other gene editing technologies in treating genetic disorders and cancers are trending, highlighting their potential for future therapies.
  6. Role of Non-Coding RNAs in Disease:
    Research into the functions and mechanisms of long non-coding RNAs (lncRNAs) and circular RNAs in various diseases is on the rise, emphasizing their potential as biomarkers and therapeutic targets.
  7. Microbiome and Human Health:
    Explorations of the relationship between the microbiome and various diseases, including metabolic and autoimmune conditions, are becoming a significant focus.
  8. Neuroinflammation and Neurodegeneration:
    Research on the mechanisms of neuroinflammation and its role in neurodegenerative diseases is gaining importance, reflecting a broader understanding of brain health.

Declining or Waning

While 'Genes & Diseases' continues to expand its focus on various emerging themes, certain areas appear to be experiencing a decline in prominence. These waning scopes may reflect shifts in research priorities or advancements in scientific understanding.
  1. Traditional Genetic Association Studies:
    While genetic association studies remain important, there has been a noticeable shift toward more integrative approaches that combine genomics with other omics data, leading to a decline in standalone genetic association studies.
  2. Basic Mechanistic Studies Without Clinical Relevance:
    Research that focuses solely on basic mechanisms without a clear clinical application or relevance is becoming less frequent, as the journal prioritizes studies with translational potential.
  3. Single-Factor Analyses in Complex Diseases:
    There is a decrease in studies that analyze single genetic or molecular factors in complex diseases, with a growing preference for multi-factorial and systems biology approaches.
  4. Historical Reviews on Established Diseases:
    Reviews focusing on well-established diseases without new insights or perspectives are waning, as the journal seeks fresh, innovative content that addresses current research gaps.

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