Cellular & Molecular Immunology
Scope & Guideline
Connecting Research, Practice, and Progress in Immunology
Introduction
Aims and Scopes
- Cellular Immunology:
Research on the roles and functions of various immune cells, including T cells, B cells, and innate lymphoid cells, in immune responses, autoimmunity, and cancer. - Molecular Mechanisms:
Studies investigating the molecular pathways and signaling mechanisms that regulate immune cell activation, differentiation, and function, particularly in the context of infections and diseases. - Immunotherapy and Vaccination:
Exploration of novel therapeutic strategies, including the development of vaccines and immunotherapies targeting cancer and infectious diseases, as well as understanding immune evasion mechanisms. - Neuroimmunology:
Research on the interactions between the immune system and the nervous system, particularly how immune responses can influence neurological diseases and vice versa. - Metabolism and Immunity:
Investigations into how metabolic processes affect immune cell function, including the impact of metabolic disorders on immune responses and the role of immune cells in metabolic regulation. - Inflammation and Autoimmunity:
Studies focusing on the mechanisms of inflammation and their contribution to autoimmune diseases, including the identification of potential therapeutic targets.
Trending and Emerging
- Personalized Immunotherapy:
A rising focus on personalized approaches to immunotherapy, including CAR-T cell therapies and individualized vaccine strategies, to enhance treatment efficacy against various cancers and infectious diseases. - Microbiome and Immunity:
An increasing interest in the interplay between the microbiome and the immune system, particularly how gut microbiota influence immune responses and disease susceptibility. - Inflammation and Immune Metabolism:
Emerging research is highlighting the connection between metabolic pathways and immune function, particularly how metabolic reprogramming can affect immune cell behavior in both health and disease. - Long-COVID and Post-Viral Immunity:
Growing attention is being paid to the immune responses associated with long-term effects of COVID-19 and other viral infections, providing insights into post-viral syndromes and therapeutic strategies. - Neuroimmune Interactions:
A trend towards understanding the bidirectional interactions between the immune system and the nervous system, especially in the context of neurodegenerative diseases and mental health.
Declining or Waning
- Basic Mechanistic Studies:
There appears to be a gradual decline in purely basic studies focusing on immune cell mechanisms without translational relevance, as the field shifts towards applications in clinical settings and therapeutic developments. - In vitro Models:
The use of traditional in vitro models for studying immune responses is becoming less prominent, with a growing preference for in vivo studies and translational research that better reflects human physiology. - Historical Perspectives:
Papers focusing on historical narratives or retrospective analyses of immunological discoveries seem to be less frequent, as the journal emphasizes current advancements and future directions.
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