COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Scope & Guideline

Fueling Discovery with Comprehensive Chemical Methodologies

Introduction

Welcome to the COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN1386-2073
PublisherBENTHAM SCIENCE PUBL LTD
Support Open AccessNo
CountryUnited Arab Emirates
TypeJournal
Convergefrom 1998 to 2024
AbbreviationCOMB CHEM HIGH T SCR / Comb. Chem. High Throughput Screen
Frequency10 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES

Aims and Scopes

The journal 'Combinatorial Chemistry & High Throughput Screening' focuses on the advancement of combinatorial chemistry and high-throughput screening methodologies in drug discovery and related fields. Its aims include fostering the development of novel therapeutic agents through innovative chemical and biological techniques.
  1. Combinatorial Chemistry Techniques:
    The journal emphasizes the use of combinatorial chemistry to synthesize a diverse range of compounds, facilitating the discovery of new drugs and bioactive molecules.
  2. High-Throughput Screening:
    Focus on high-throughput screening methodologies to rapidly assess the biological activity of large compound libraries, enabling efficient identification of lead compounds.
  3. Network Pharmacology:
    Integration of network pharmacology approaches to elucidate the mechanisms of action of compounds, including their interactions within biological networks.
  4. Experimental Validation:
    Encouragement of experimental validation of findings from combinatorial and high-throughput screening studies, ensuring that theoretical predictions are supported by empirical data.
  5. Natural Product Research:
    Investigation of natural products and their derivatives as potential therapeutic agents, leveraging traditional knowledge and modern analytical techniques.
The journal has seen a rise in certain themes reflecting the evolving landscape of pharmaceutical research. These emerging scopes indicate where the focus is shifting within the field.
  1. Integrative Multi-Omics Approaches:
    There is a growing trend towards using integrative multi-omics approaches, combining genomics, proteomics, and metabolomics to provide comprehensive insights into drug mechanisms and biological effects.
  2. Artificial Intelligence in Drug Discovery:
    The incorporation of artificial intelligence and machine learning techniques for predicting drug interactions, optimizing compounds, and analyzing biological data is rapidly gaining traction.
  3. Bioinformatics and Computational Modeling:
    An increase in studies utilizing bioinformatics tools and computational modeling to predict drug activity and interactions, reflecting a shift towards data-driven research.
  4. Ethnopharmacology and Natural Products:
    Revitalized interest in ethnopharmacology and the exploration of natural products as therapeutic agents, focusing on their bioactive compounds and mechanisms of action.
  5. Targeted Therapies and Personalized Medicine:
    Growing focus on targeted therapies and personalized medicine approaches, highlighting the importance of tailored treatments based on individual patient profiles.

Declining or Waning

While certain areas remain strong, there are emerging trends that suggest a decline in others within the journal's scope. The following themes show waning interest or publication frequency.
  1. Traditional Medicinal Practices:
    Research focused on traditional medicinal practices and their integration with modern pharmacological approaches appears to be declining, as the journal shifts towards more contemporary methodologies.
  2. Single-target Drug Discovery:
    There is a noticeable decrease in studies solely focusing on single-target drug discovery, as the field increasingly recognizes the complexity of biological systems and the need for multi-target approaches.
  3. Basic Pharmacology Studies:
    Basic pharmacology studies without a clear connection to combinatorial chemistry or high-throughput screening seem to be less prevalent, reflecting a shift towards more applied research.
  4. In vitro Studies without Integration:
    Research that does not integrate in vitro findings with computational or network pharmacology approaches is becoming less common, as the field moves towards more holistic methodologies.

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